克罗恩病患者睡眠质量与疾病活动度及负性情绪的相关性探讨

Study on the Relativity of Sleep Quality and Disease Activity and Negative Emotion in Crohn’s Disease Patients

为探讨克罗恩病(CD)患者睡眠质量与疾病活动度及负性情绪的相关性,选取我院收治的101例CD患者作为观察对象,分别采用匹兹堡睡眠质量指数量表(PSQI)、疾病活动指数(DAI)量表及汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)对患者睡眠质量、疾病活动度及焦虑、抑郁程度进行测评,并采用Pearson相关分析或Spearman相关分析法分析三者之间的相关性。结果显示,本组CD患者67例(66.34%)出现睡眠障碍。101例CD患者PSQI总分为(8.41±2.27)分;DAI总分为(159.86±34.87)分;HAMA总分为(7.80±2.29)分,表示可能存在焦虑;HAMD总分为(8.72±2.49)分,表示处于轻度抑郁状态。相关性分析显示,CD患者PSQI总分及各分项得分与DAI总分、HAMA总分、HAMD总分均具有相关性,呈正相关,P<0.05。结果表明,CD患者睡眠质量与疾病活动度及负性情绪具有相关性,通过改善患者睡眠质量,有可能有助于缓解病情及不良情绪。

This study was to explore the relativity of sleep quality and disease activity and negative emotion in Crohn’s disease(CD)patients,enrolled 101 CD patients treated in author’s hospital into the study:to measure and to assess their sleep quality,disease activity,as well anxiety and depression degree by using PSQI,DAI,as well HAMA and HAMD;and,to analyse the relativity between above three indexes by using Pearsonor Spearman analysis.As results,67 cases(67/101,66.34%)suffered from sleep disorder;in the101 cases their PSQI total points were(8.41±2.27),DAI total points were(159.86±34.87),HAMA total points were(7.80±2.29)showed they could be at anxity;HAMD total points were(8.72±2.49)could be at mild depression.Relativity analysis showed there was the relativity of PSQI total points and all sub-item points to the total points of DAI,of HAMA,and of HAMD,and this relativity belongs to proportional one(P<0.05).Results show that in CD patients there is a relativitly of sleep quality and disease activity and patients’negative emotion;to improve patients’sleep quality could be helpful to relieve disease condition and poor emotion.