乳腺癌与甲状腺疾病关系研究进展

Progress of the relationship between breast cancer and thyroid diseases

乳腺癌与甲状腺疾病均好发于女性,严重影响女性的身心健康。乳腺癌患者在发病前后罹患甲状腺疾病的风险较其他恶性肿瘤高,两者之间存在着一些共同的危险因素,且乳腺和甲状腺同属于激素应答性器官,在一些调控通路之间两者也能相互影响。目前认为碘、甲状腺激素受体和雌激素受体是乳腺癌与甲状腺疾病关系密切可能的发病机制。文章通过分析近年来乳腺癌与甲状腺良性疾病、甲状腺癌、甲状腺激素及抗体关系的研究,探讨乳腺癌与甲状腺疾病之间的关系,为疾病的防治提供依据。

Breast cancer and thyroid diseases mostly occur in women,and both have seriously affected women's physical and mental health.Breast cancer patients have a higher risk of thyroid diseases before and after the onset of the disease compared with other malignant tumors.There are some common risk factors between them,and breast and thyroid are hormone-responsive organs,so they can also influence each other in some regulatory pathways.Iodine,thyroid hormone receptor and estrogen receptor are considered to be the possible pathogenesis of breast cancer.This paper explores the relationship between breast cancer and thyroid diseases with the help of researches in breast cancer,thyroid benign diseases,thyroid cancer,thyroid hormones and antibodies in recent years,so as to provide a basis for disease prevention and treatment.