超声造影与MRI对乳腺癌患者腋窝淋巴结诊断价值

Diagnostic Value of Contrast Ultrasound and MRI for Axillary Lymph Nodes in Patients with Breast Cancer

目的比较超声造影和MRI对乳腺癌患者腋窝淋巴结诊断价值。方法回顾分析常规超声诊断为乳腺癌患者的腋窝淋巴结超声造影与MRI影像学资料,以临床病理结果为"金标准",比较两种方法诊断腋窝淋巴结转移的价值。结果病理结果显示97枚腋窝淋巴结中,淋巴结转移69枚,淋巴结无转移28枚;超声造影诊断乳腺癌患者腋窝淋巴结转移的灵敏度、特异度、准确率分别为79.71%、96.43%、84.54%;MRI诊断乳腺癌患者腋窝淋巴结转移的灵敏度、特异度、准确率分别为88.41%、92.86%、89.69%;超声造影结果显示腋窝淋巴结转移组的SImax-SImin显著高于无转移组(P<0.05),MRI结果显示腋窝淋巴结转移组的淋巴结短径、长径及皮质厚度均高于无转移组(P<0.05)。结论两种方法均可有效诊断乳腺癌患者腋窝淋巴结转移,可以依据检查方法的特点为患者选择合适的诊断方法。

Objective To compare the diagnostic value of contrast ultrasound and MRI for axillary lymph nodes in patients with breast cancer. Methods A retrospective analysis was performed on contrast ultrasound and MRI imaging data of axillary lymph nodes in patients who were diagnosed as breast cancer by routine ultrasound. Taking clinical pathological results as golden standard, the diagnostic value of the two methods for axillary lymph node metastasis was compared. Results The pathological results showed that there were 69 lymph node metastasis, and 28 without lymph node metastasis in the 97 axillary lymph nodes. The sensitivity, specificity and accuracy of contrast ultrasound in diagnosis of axillary lymph node metastasis of breast cancer patients were 79.71%, 96.43% and 84.54%, respectively. The above 3 indexes of MRI were 88.41%, 92.86%, and 89.69%, respectively. The contrast ultrasound results showed that SImax-SImin in the axillary lymph node metastasis group was significantly higher than that in non-metastasis group(P<0.05). MRI results showed that short diameter and long diameter of axillary lymph nodes and cortical thickness in the axillary lymph node metastasis group were higher than those in non-metastasis group(P<0.05). Conclusion Both methods can effectively diagnose axillary lymph node metastasis of breast cancer patients. The appropriate diagnostic methods can be selected according to the features of examination methods.