CEUS和MRI评价高强度聚焦超声治疗子宫肌瘤的效果对比

Evaluation of The Effects of High-intensity Focused Ultrasound in the Treatment of Uterine Fibroids by CEUS and MRI

目的对比观察超声造影(CEUS)和核磁共振成像(MRI)评价高强度聚焦超声(HIFU)治疗子宫肌瘤的效果。方法选择2015年5月~2018年5月期间在我院行HIFU治疗的186例子宫肌瘤患者,治疗前后均行CEUS和增强MRI检查。结果186例患者均成功完成HIFU治疗,CEUS检查与MRI检查均可清楚显示肌瘤及HIFU后无灌注范围。CEUS检查对肌瘤最大径、肌瘤体积、无灌注区最大径、无灌注区体积及消融率的评估与MRI检查结果比较,差异无统计学意义(P>0.05)。Spearman相关性分析显示CEUS检查与MRI检查结果有显著相关性。结论CEUS检查可清楚显示肌瘤及非灌注区情况,与增强MRI检查结果高度一致,可为HIFU治疗子宫肌瘤疗效评估及临床治疗方案的制定提供可靠依据。

Objective To compare contrast-enhanced ultrasonography(CEUS) and magnetic resonance imaging(MRI) in evaluation of the effects of high-intensity focused ultrasound(HIFU) in the treatment of uterine fibroids. Methods A retrospective analysis was performed on 186 patients with uterine fibroids who underwent HIFU in the hospital during the period from May 2015 to May 2018. CEUS and enhanced MRI were performed before and after treatment. Results All patients were successfully treated with HIFU. Both CEUS and MRI clearly showed fibroids and non-perfusion range after HIFU. There was no significant difference in the maximum diameter or volume of fibroids, the maximum diameter or volume of non-perfusion area or ablation rate between CEUS and MRI(P>0.05). Spearman correlation analysis showed a significant correlation between CEUS and MRI findings. Conclusion CEUS can clearly show the condition of fibroids and non-perfusion area. The results are highly consistent with those of enhanced MRI. It can provide a reliable basis for evaluation of the curative effect of HIFU on uterine fibroids and the development of clinical treatment plan.