PET/CT、CT在诊断口腔鳞癌颈部淋巴结转移中的应用观察

Application of PET/CT and CT in the Diagnosis of Cervical Lymph Node Metastasis of Oral Squamous Cell Carcinoma

目的探讨正电子发射计算机断层扫描(PET-CT)、CT检查在口腔鳞癌(OSCC)患者颈部淋巴结转移中的应用价值。方法收集2017年1月-2018年12月在我院经手术病理明确诊断的OSCC患者98例,术前均行PET-CT、CT检查,以手术病理结果为金标准,分析两种检查方法对颈部淋巴结转移的敏感度、特异度、准确度等差异。结果 98例OSCC患者,术后病理证实颈部淋巴结阳性者38例,阴性者60例。术前PET/CT诊断OSCC患者颈部淋巴结转移的敏感度、特异度、准确度、阳性预测值、阴性预测值分别为81.58%、80.00%、80.61%、72.09%、87.27%,高于CT检查的76.32%、73.33%、74.49%、64.44%、83.02%,但差异均无统计学意义(P>0.05)。结论 PET/CT对于OSCC颈部淋巴结转移的诊断有重要价值,较CT检查有一定优势。

Objective To explore the application value of positron emission tomographycomputed tomography(PET-CT) and CT in the diagnosis of cervical lymph node metastasis in patients with oral squamous cell carcinoma(OSCC). Methods 98 patients with OSCC who were confirmed by surgical pathology in our hospital from January 2017 to December 2018 were selected. All patients were given PET-CT and CT before operation. The surgical pathological results were used as the gold standards to analyze the sensitivity, specificity and accuracy of cervical lymph node metastasis. Results Among the 98 patients with OSCC, there were 38 cases of positive cervical lymph nodes and 60 cases of negative cervical lymph nodes confirmed by postoperative pathology. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of preoperative PET/CT were 81.58%, 80.00%, 80.61%, 72.09% and 87.27% respectively in the diagnosis of cervical lymph node metastasis in OSCC patients, which were higher than those of CT examination with 76.32%, 73.33%, 74.49%, 64.44% and 83.02%(P>0.05). Conclusion PET/CT is of great value in the diagnosis of cervical lymph node metastasis of OSCC, and has certain advantages over CT examination.