PETCT在宫颈癌腹膜淋巴结转移患者放疗中的应用观察

Application of PETCT in Radiotherapy for Patients with Cervical Cancer Peritoneal Lymph Node Metastasis

目的观察正电子发射计算机断层显像(PETCT)在宫颈癌腹膜淋巴结转移患者放疗中的应用价值。方法选取2018年3月~2019年3月本院收治的72例宫颈癌腹膜淋巴结转移患者为研究对象,按照入院顺序编号随机分为对照组(CT引导下放疗治疗)和观察组(PETCT引导下放疗治疗)各36例,比较两组化疗相关指标、近期疗效及不良反应发生情况。结果观察组GTVnd、CTV、PTV较对照组明显大,差异显著(P<0.05),两组PGTVnd比较差异无统计学意义(P>0.05);观察组近期化疗总有效率明显高于对照组(86.11%vs70.73%,P<0.05),两组不良反应发生率相比较无明显差异(P>0.05)。结论 PETCT在宫颈癌腹膜淋巴结转移患者放疗中具有明确的应用优势,能够精准定位转移淋巴结以提高放疗疗效,且安全性好。

Objective To observe the application value of positron emission tomographycomputed tomography(PETCT) in radiotherapy for patients with cervical cancer peritoneal lymph node metastasis. Methods 72 patients with cervical cancer peritoneal lymph node metastasis who were admitted to the hospital from March 2018 to March 2019 were enrolled in the study. They were randomly divided into control group(CT-guided radiotherapy) and observation group(PETCT guided radiotherapy) by admission order, 36 cases in each group. The chemotherapy-related indexes, shortterm curative effects and occurrence of adverse reactions were compared between the two groups. Results GTVnd, CTV and PTV in observation group were significantly larger than those in control group(P<0.05). There was no significant difference in PGTVnd between the two groups(P>0.05). The total response rate of short-termchemotherapy in observation group was significantly higher than that in control group(86.11%vs70.73%, P<0.05). There was no significant difference in incidence of adverse reactions between the two groups(P>0.05). Conclusion There are clear application advantagesof PETCT in radiotherapy for patients with cervical cancer peritoneal lymph node metastasis. It can accurately locate metastatic lymph nodes to improve curative effect of radiotherapy, with good safe.