无创呼吸机对慢性阻塞性肺疾病合并呼吸衰竭的治疗效果研究

Study on the therapeutic effect of noninvasive ventilator on chronic obstructive pulmonary disease with respiratory failure

目的探讨无创呼吸机对慢性阻塞性肺疾病合并呼吸衰竭的治疗效果。方法选取2017年6月至2019年3月在本院治疗的104例慢阻肺合并呼吸衰竭患者,随机分为观察组与对照组,各52例。对照组患者给予常规治疗,观察组在对照组的基础上给予无创呼吸机治疗,观察并比较两组患者临床治疗效果、生命体征相关指标、不良反应发生率。结果观察组治疗效果(94.23%)优于对照组(71.15%),差异有统计学意义(P<0.05);治疗前,两组患者生命体征相关指标比较差异无统计学意义,治疗后,两组患者各项指标与治疗前比较均有所改善,差异有统计学意义(P<0.05),且观察组患者各项指标的改善情况均优于对照组,差异有统计学意义(P<0.05);观察组不良反应发生率(5.77%)低于对照组(30.77%),差异有统计学意义(P<0.05)。结论临床上治疗慢性阻塞性肺疾病合并呼吸衰竭患者时,在基础治疗的同时给予患者无创呼吸机治疗,能够有效改善患者各项生命体征,降低不良反应发生率,效果显著,值得临床推广。

Objective To explore the therapeutic effect of noninvasive ventilator on COPD with respiratory failure. Methods 104 patients with COPD and respiratory failure who were treated in our hospital from June 2017 to March 2019 were randomly divided into observation group and control group, with 52 cases in each groups. The patients in the control group were given routine treatment, while the patients in the observation group were given noninvasive ventilator treatment on the basis of the control group. To observe and compare the clinical treatment effect, vital signs and the incidence of adverse reactions between the two groups. Results The therapeutic effect of the observation group(94.23%) was better than that of the control group(71.15%), and the difference was statistically significant(P<0.05). Related parameters of vital signs before the treatment, there was no statistically significant difference between two groups, after treatment, the indicators compared with before treatment in both groups were improved,the difference was statistically significant(P<0.05), and patients improve the indicators of observation group were better than control group, the difference was statistically significant(P<0.05). The incidence of adverse reactions in the observation group(5.77%) was lower than that in the control group(30.77%), and the difference was statistically significant(P<0.05). Conclusion In the clinical treatment of COPD patients with respiratory failure, the basic treatment and non-invasive ventilator treatment can effectively improve the vital signs of patients, reduce the incidence of adverse reactions, the effect is significant, it is worthy of clinical promotion.