预防性新鲜冰冻血浆输注用于产后出血救治中的效果及对患者凝血功能的影响

Effect of preventive fresh frozen plasma infusion in the treatment of postpartum hemorrhage and its effect on coagulation function of patients

目的探讨产后出血救治中使用预防性新鲜冰冻血浆输注的效果及对患者凝血功能的影响。方法选取2018年1月到2019年4月本院收治的产后出血需实施成分输血治疗的产妇80例作为研究对象,随机分为常规组(40例,常规新鲜冰冻血浆输注)和预防性组(40例,预防性新鲜冰冻血浆输注)。分析两组产妇止血效果、恢复状况、输血状况、凝血功能状况。结果预防性组产妇产后出血量,产后住院时间,血浆、红细胞、血小板、冷沉淀输注量均低于对照组(P<0.05)。治疗后,预防性组活化部分凝血活酶时间、凝血酶原时间、纤维蛋白原、血小板计数与常规组比较差异无统计学意义。结论产后出血救治中使用预防性新鲜冰冻血浆输注可有效改善凝血功能,保证止血效果,减少输血量,促进产妇早日恢复。

Objective To investigate the effect of prophylactic fresh frozen plasma infusion in the treatment of postpartum hemorrhage and its effect on the coagulation function of patients. Methods 80 cases from January 2018 to April 2019 in our hospital with postpartum hemorrhage who needed component blood transfusion were enrolled in the study. They were randomly divided into routine group(40 cases, routine fresh frozen plasma transfusion) and preventive group(40 cases, preventive fresh frozen plasma transfusion). The hemostatic effect, recovery, blood transfusion and coagulation function were analyzed. Results The amount of postpartum hemorrhage, postpartum hospitalization time, plasma, erythrocyte, platelet and cryoprecipitate transfusion in the prophylactic group were lower than those in the conventional group(P<0.05). There was no significant difference in activated partial thromboplastin time, prothrombin time, fibrinogen and platelet count between the prophylactic group and the conventional group. Conclusion Preventive fresh frozen plasma infusion in the treatment of postpartum hemorrhage can effectively improve coagulation function, ensure hemostasis effect, reduce blood transfusion volume and promote early recovery of puerpera.