子午流注开穴法治疗睡眠障碍

Midnight-noon ebb-flow acupoint-opening method in the treatment of sleep disorder

目的探讨子午流注开穴法治疗睡眠障碍的临床应用及其疗效。方法选取2013年1月至2015年12月就诊的睡眠障碍患者60例,按照随机数字表法分为观察组和对照组,每组30例。对照组口服常规药物佐匹克隆片治疗。观察组采用子午流注开穴法针灸治疗。比较两组患者的临床疗效。采用国际公认的匹兹堡睡眠质量指数量表(PSQI)评估患者的睡眠质量。记录两组的入睡时间、晚间觉醒次数、睡眠时间。检测两组治疗前后促肾上腺皮质激素释放激素(CRH)、促肾上腺皮质激素(ACTH)、促甲状腺激素释放激素(TRH)的水平。结果观察组的总有效率稍高于对照组,但差异无统计学意义(P>0.01)。治疗后两组PSQI评分明显降低(P均<0.05),观察组低于对照组(P<0.01)。治疗后两组入睡时间、晚间觉醒次数减少,睡眠时间升高(P均<0.05);观察组治疗后的入睡时间、晚间觉醒次数低于对照组,睡眠时间长于对照组(P均<0.05)。两组治疗后的CRH、ACTH、TRH水平明显降低(P均<0.05);观察组治疗后的CRH、ACTH、TRH水平比对照组降低(P均<0.05)。结论子午流注开穴法可提高睡眠障碍的疗效,改善患者的睡眠质量。

Objective To explore the clinical application and effect of midnight-noon ebb-flow(Ziwu Liuzhu)acupointopening method in the treatment of sleep disorders.Methods Sixty patients with sleep disorders treated from January 2013 to December 2015,were randomly divided into observation group and control group(n=30,each).The routine treatment with zopiclone tablets was given in control group,and acupuncture and moxibustion with MNEF opening acupoint method was performed in observation group.The internationally recognized Pittsburgh Sleep Quality Index(PSQI)was used to evaluate the sleep quality of patients,including the time of falling asleep,the times of awakening at night and the time of sleep.The levels of corticotropin releasing hormone(CRH),adrenocorticotropic hormone(ACTH)and thyroid stimulating hormone releasing hormone(TRH)were detected before and after treatment in both groups.Results The total effective rate in observation group was slightly higher than that in control group,but the difference was not statistically significant(P>0.05).After treatment,PSQI score significantly decreased in both groups(all P<0.05)and was statistically lower in observation group than that in control group(all P<0.05);the time of falling asleep and the times of awakening at night significantly decreased,and the time of sleep increased in two groups(all P<0.05);compared with control group,the time of falling asleep and the times of awakening at night were significantly shortened,and the time of sleep was extended in observation group(all P<0.05).After treatment,the levels of CRH,ACTH and TRH significantly decreased in both groups(all P<0.05)and were statistically lower in observation group than those in control group(all P<0.05).Conclusion Midnight-noon ebb-flow acupoint-opening method can improve the therapeutic effect in treating sleep disorders and the quality of sleep.