影响汉中地区HCV感染的相关因素分析

Analysis of the related factors affecting HCV infection in Hanzhong region

目的分析影响汉中地区丙型肝炎病毒(HCV)感染的危险因素。方法按照1∶1病例-对照配对原则,选择2017年10月至2019年10月登记在册的300例HCV感染患者(研究组)和同期300例无慢性感染性疾病的志愿者(对照组)为研究对象。利用单因素分析和多因素Logistic回归分析法观察影响该地区HCV感染的相关危险因素。结果单因素分析显示,研究组初中及以下文化程度及具有手术史、针灸、创伤性美容、血液透析史、输血或血液制品使用行为者占比显著高于对照组(P<0.05)。多因素Logistic回归分析显示,文化程度、创伤性美容、血液透析史、输血或血液制品使用是HCV感染发生的独立危险因素(P<0.05)。结论文化程度、创伤性美容、血液透析、输血或血液制品使用是影响汉中地区HCV感染的独立危险因素,应加强该地区传染性疾病的宣传预防,提高居民文化水平和整体素质,规范美容行业的公共卫生,强调血液透析和输血或血液制品使用的安全。

Objective To analyze the risk factors affecting hepatitis C virus(HCV)infection in Hanzhong region.Methods According to the principle of 1∶1 case-control pairing,300 HCV infected patients(study group)registered from October2017 to October 2019 and 300 volunteers(control group)without chronic infectious diseases in the same period were selected as the study objects.Univariate and multivariate Logistic regression analysis were used to observe the relevant risk factors affecting HCV infection in the region.Results The univariate analysis showed that the proportions of people with junior high school education and below and people with surgery history,acupuncture,traumatic cosmetology,history of hemodialysis,blood transfusion or blood products use in the study group were significantly higher than those in the control group(P<0.05).The multivariate Logistic regression analysis showed that education,traumatic cosmetology,hemodialysis history,blood transfusion or use of blood products were independent risk factors for HCV infection(P<0.05).Conclusion Education,traumatic cosmetology,hemodialysis history,blood transfusion or use of blood products are independent risk factors for HCV infection in Hanzhong region.We should strengthen the propaganda and prevention of infectious diseases in this area,improve the cultural level and overall quality of residents,standardize the public health of cosmetology industry,and emphasize the safety of hemodialysis,blood transfusion or use of blood products.