不同分娩镇痛方式对产妇泌乳素的影响

Effects of Different Labor Analgesic Methods on Maternal Prolactin

目的研究不同分娩镇痛方式对产妇泌乳素的影响。方法根据"双盲随机分组原则"将2017年1月至2017年12月期间在本院分娩的产妇72例分为对照组和观察组,36例/组,前一组采取硬膜外麻醉分娩镇痛,后一组实施瑞芬太尼静脉分娩镇痛。将两组产妇的血浆泌乳素水平、乳汁分泌量、VSA评分、不良反应发生情况进行比对。结果观察组产妇分娩后的血浆泌乳素水平均高于对照组,乳汁分泌量大于对照组,P<0.05;观察组产妇宫口开至5cm、8cm、10cm时的VSA评分均低于对照组数据(P<0.05),观察组和对照组之间对比不良反应发生情况差别不大(P>0.05)。结论同硬膜外麻醉分娩镇痛相比,芬太尼静脉分娩镇痛有助于产妇血浆泌乳素分泌、乳汁分泌量的增加,可缓解产妇的疼痛程度,且安全性较高。

objective to study the effects of different labor analgesia on maternal prolactin. Methods according to the "double-blind randomization principle", 72 cases of parturient women delivered in our hospital from January 2017 to December 2017 were divided into control group and observation group, with 36 cases/group. The former group received epidural anesthesia for labor analgesia, and the latter group received remifentanil for intravenous labor analgesia. Plasma prolactin level, milk secretion, VSA score and adverse reactions were compared between the two groups. Results the plasma prolactin level in the observation group was higher than that in the control group, and the milk secretion was greater than that in the control group(P < 0.05). The VSA score at 5 cm, 8 cm and 10 cm in the observation group was lower than that in the control group(P<0.05). There was no significant difference in the incidence of adverse reactions between the observation group and the control group(P>0.05). Conclusion compared with epidural anesthesia for labor analgesia, fentanyl intravenous labor analgesia contributes to the increase of maternal plasma prolactin secretion and milk secretion, and can relieve maternal pain.