基因组——了解新型冠状病毒的最直接手段

Virus genome,the direct way to know the SARS-CoV-2virus

2020年3月11日WHO宣布新型冠状病毒肺炎为"全球流行病"。理解新型冠状病毒基因组,阐明深藏在病毒背后的科学问题,将为控制疫情传播提供重要的科学依据。作者阐述了解析病毒基因组能够有助于进行病原鉴定、基因分析、病毒溯源、传播动态、疫情预判等重要工作,同时也提出了目前新型冠状病毒病毒基因组研究的重点方向,以及加强国内外交流的重要意义。

WHO announced the COVID-19 epidemic as a global pandemic on 11 March 2020.Understanding the genome of the pathogen SARS-CoV-2 virus,and unravelling the science behind the virus will pave the way for controlling the disease.This manuscript summarized the aspects that virus genome could contribute to,including virus identification,essential gene analysis,virus origination,transmission dynamics,and epidemic prediction.Meanwhile,key directions of SARS-CoV-2 virus genomics in the current stage,and the importance of communication and collaboration are stated.