摘要
IgA肾病是一种常见的且最终会导致终末期肾脏病的原发性肾小球疾病。中医认为IgA肾病大部分都是血瘀症型,化瘀通络治疗是IgA肾病治疗的重要方法之一。现基于PI3K/Akt/mTOR通路探讨水蛭对IgA肾病的作用机制及近几年的研究进展进行总结,以期为临床防治IgA慢性肾脏病肾纤维化提供更加真实有效的数据。
IgA nephropathy is a common primary glomerular disease that leads to end-stage renal disease.Traditional Chinese medicine believes that most IgA nephropathy is blood stasis type,and removing blood stasis and clearing collaterals therapy is one of the important methods for IgA nephropathy treatment.Now,based on the PI3K/Akt/mTOR pathway,the mechanism of leech on IgA nephropathy and the research progress in recent years are summarized,so as to provide more real and effective data for the clinical prevention and treatment of renal fibrosis in IgA chronic kidney disease.
作者
曹响
谢丽萍
赵洁
江志雄
徐霜霜
Cao Xiang;Xie Liping;Zhao Jie;Jiang Zhixiong;Xu Shuangshuang(Guangxi University of Traditional Chinese Medicine,Nanning 530001,China;Department of Nephrology,the First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine,Nanning 530023,China)
出处
《亚太传统医药》
2020年第2期181-184,共4页
Asia-Pacific Traditional Medicine
基金
广西自然科学基金项目(2014GNXSFAA118247)
广西中医药大学研究生教育创新计划(YCSY2018023)。
