妊娠期糖尿病患者血、尿生化指标与尿路结石发生的相关指标分析

Analysis of Correlation between Blood and Urine Biochemical Indexes and Urinary Calculus in Gestational Diabetes Mellitus

目的探讨妊娠期糖尿病患者血、尿生化指标与尿路结石发生的相关指标分析。方法选取妊娠期糖尿病尿结石患者85例为观察组,选取同期无尿结石的糖尿病妊娠妇女80例为对照组,全部研究对象均接受血、尿生化相关指标检测,应用SPSS17.0软件实施统计学处理,比较两组血液指标和尿液指标异常率。结果观察组血液葡萄糖(B-Glu)水平为5.08±5.00mmol/L,对照组为5.19±5.18mmol/L,差异无统计学意义(t=0.414,P>0.05)。观察组B-WBC[(11.38±3.90)×10^9/Lvs (6.18±1.50)×10^9/L,t=136.625],B-PO4(1.69±0.18mmol/L vs 1.19±0.14mmol/L,t=10.375),B-UA(328.35±207.15mmol/L vs 280.83±68.51mmol/L,t=6.308)高于对照组,B-Ca(2.25±0.17mmol/L vs 2.38±0.15mmol/L,t=14.856)和B-Mg(0.84±0.22mmol/L vs 0.91±0.20mmol/L,t=17.724)水平低于对照组,差异均有统计学意义(均P<0.05),两组B-Ca异常率差异无统计学意义(χ^2=0.841,P>0.05)。观察组B-WBC,B-UA,B-PO4,B-Mg和B-Glu异常率均高于对照组,差异具有统计学意义(χ^2=115.64,12.215,12.215,8.627,7.441,均P<0.05)。观察组U-LEU,U-KET,U-ERY,U-PRO和U-Glu异常率均高于对照组,差异具有统计学意义(χ^2=42.655,44.620,68.641,42.775,24.813,均P<0.05)。结论高磷低镁血症、尿路感染以及糖尿病均会影响妊娠期尿结石的发生。

Objective To investigate the correlation between blood and urine biochemical indexes and urinary calculus in gestational diabetes mellitus. Methods 85 patients with gestational diabetes urinary calculi were selected as the observation group. 80 diabetic pregnant women without urinary stones admitted to the same period were selected as the control group. All the subjects received blood and urine biochemical related indicators. Detection, SPSS17.0 software was used to implement statistical processing, and the abnormal rates of blood and urine indicators were compared between the two groups. Results The B-Glu level in the observation group was 5.08±5.00 mmol/L, and the control group was 5.19±5.18 mmol/L. The difference was not statistically significant(t=0.414, P>0.05). The observation group B-WBC[(11.38±3.90)×10^9/L vs(6.18±1.50)×10^9/L, t=136.625], B-PO4(1.69±0.18 mmol/L vs 1.19±0.14 mmol/L, t=10.375), B-UA(328.35±207.15 mmol/L vs 280.83±68.51 mmol/L, t=6.308) was higher than the control group, B-Ca(2.25±0.17 mmol/L vs 2.38±0.15 mmol/L, t=14.856) and B-Mg(0.84±0.22 mmol/L vs 0.91±0.20 mmol/L, t=17.724) were lower than the control group, and the difference was statistically significant(all P<0.05). There was no significant difference in abnormal rate of B-Ca(χ^2=0.841,P>0.05). The abnormal rates of B-WBC, B-UA, B-PO4, B-Mg and B-Glu in the observation group were higher than those in the control group, and the difference was statistically significant(χ^2=115.64,12.215,12.215,8.627,7.441,all P<0.05). The abnormal rates of U-LEU, U-KET, U-ERY, U-PRO and U-Glu in the observation group were higher than those in the control group, and the difference was statistically significant (χ^2=42.655,44.620,68.641,42.775,24.813,all P<0.05).Conclusion Hyperphosphatemia and hypomagnesemia, urinary tract infection and diabetes mellitus all can affect the occurrence of urinary calculi during pregnancy.