摘要
目的研究神仙草醇提物对大鼠肠系膜上动脉血管舒张作用的影响。方法采用四通道微血管张力测定动态描记系统,检测神仙草醇提物在高钾(KPSS)、5-羟色胺(5-HT)、苯肾上腺素(PE)作用后对完整内皮血管环或无内皮血管环的舒张作用。结果神仙草醇提物对5-羟色胺作用的血管舒张作用最大,对高钾作用的血管舒张作用最小。结论神仙草醇提物对大鼠肠系膜上动脉血管具有一定的舒张作用。
Objective To investigate the vasodilation effect of the alcohol extract from Abelia engleriana(Graebn.)Rehd.on rats.Methods The graph is used to study the relaxation effect of the alcohol extract from A.engleriana on endothelium-intact or endothelium﹣denuded vascular rings after contracted by KPSS,5-HT,PE.Results The alcohol extract from A.engleriana has a significant vasodilation effect on vascular rings contracted by 5-HT and the mild vasodilation effect on vascular rings contracted by KPSS.Conclusion The alcohol extract from A.engleriana has a vasodilation effect on the rats.
作者
刘欢欢
张彦
薛璇玑
郭增军
LIU Huan-huan;ZHANG Yan;XUE Xuan-ji;GUO Zeng-jun(School of Pharmacy,Xi'an Jiaotong University,Xi'an 710061,China;Shaanxi Key Laboratory of“Qiyao”Resources and Anti-tumor Acitivities Xi'an,Xi'an 710061,China;Institute of Basic and Translational Medicine,Xi'an Medical University,Xi'an 710021,China)
出处
《现代中药研究与实践》
CAS
2020年第2期14-17,共4页
Research and Practice on Chinese Medicines
基金
西安医学院中尼友好拉吉姆医学实验室开放基金项目(18LJM05)
西安医学院2018年配套基金项目(2018PT64)
2018年中医药公共卫生服务补助资金第四次全国中药资源普查项目(财社[2018]43号)。
关键词
神仙草醇提物
舒血管作用
血管环
心脑血管疾病
Alcohol extract from Abelia engleriana(Graebn.)Rehd.
vasodilation vascular effect
vascular rings
cardiovascular and cerebrovascular diseases
