持续区域动脉灌注联合不同药物治疗重症急性胰腺炎的研究

Continuous regional arterial infusion combined with different drugs in the treatment of severe acute pancreatitis

近年来,很多研究表明持续区域动脉灌注(continuous regional arterial infusion,CRAI)在治疗重症急性胰腺炎(severe acute pancreatitis,SAP)中的优势,CRAI主要通过导管插入胰腺目标区域的供血动脉,与静脉途径和皮下注射途径相比,药物能更有效地到达胰腺,疗效好、不良反应发生率低,因此,CRAI治疗SAP相关研究近年来逐渐成为热点。本文将对CRAI联合不同药物对SAP治疗的研究进展作一概述。

In recent years,many studies have shown the advantages of continuous regional arterial infusion(CRAI)in the treatment of severe acute pancreatitis(SAP),CRAI mainly through catheter inserted into the target area for pancreas artery blood supply,compared with venous pathway and subcutaneous injection,drugs can more effectively reach to the pancreas,good curative effect,low incidence of adverse reactions,thus,CRAI therapy for related research gradually become a hot spot in recent years,in this article,CRAI current research progress of different drugs for the treatment of SAP was reported.