新型冠状病毒肺炎合并肝损伤研究现状与挑战分析

The analysis of present researches and challenges of COVID-19 with liver injury

新型冠状病毒肺炎(COVID-19)作为一种发病率高、传染性强、病情变化快的公共卫生事件,发病以来受到国内外高度关注。随着其临床特征及发病机制的研究进展,该病呼吸系统以外症状受到越来越多的重视。肝脏不仅是机体能量代谢的场所,也是重要免疫器官,是COVID-19疾病进程中受累的重要脏器之一。本文就COVID-19合并肝损伤研究现状及面临挑战作一探讨,旨在提高疫情防控中对该病的认识,减少COVID-19合并肝损伤的发生,降低不良结局的风险,为优化临床诊治方案及拓展研究思路提供一定的参考。

As a public health event,Corona Virus Disease 2019(COVID-19)is highly concerned at home and abroad since its onset because it has the characteristics of high incidence,strong contagion,and rapid changes.With the research progress of its clinical characteristics and pathogenesis,more and more attention has been paid to the symptoms outside the respiratory system.We know that liver is not only the site of energy metabolism,but also an important immune organ.In addition,it is one of the important damaged organs involved in the process of COVID-19.This article analyzed the present researches and challenges of COVID-19 with liver injury research in order to enhance the acknowledgement of this disease in epidemic prevention and control.It will help to decrease the incidence of COVID-19 with liver injury and reduce the risk of adverse outcomes,in order to provide reference for optimizing the clinical decision about diagnosis and treatment and expand the research ideals.