摘要
前列腺特异膜抗原(PSMA)是前列腺癌分子影像学研究的热点.但PSMA也可在非前列腺的生理组织及其他多种良恶性疾病中表达,特别是在肿瘤相关的新生血管内皮细胞中高表达.相关临床研究已表明PSMA配体PET显像在指导非前列腺癌的其他恶性肿瘤分期中具有应用价值.该文对PSMA配体PET显像在非前列腺肿瘤诊断和治疗中的应用进行综述.
Prostate specific membrane antigen(PSMA)is a hot topic in molecular imaging research of prostate cancer.However,non-prostate related PSMA can also be expressed in physiological tissues and different benign and malignant diseases,especially in tumor-associated endovascular endothelial cells.Related clinical studies have demonstrated the staging potential of PSMA ligands PET imaging in non-prostate tumors.This article summarizes the application of PSMA ligands PET imaging in the diagnosis and treatment of non-prostate tumors.
作者
王观筠
于鹏
宁静
徐白萱
Wang Guanyun;Yu Peng;Ning Jing;Xu Baixuan(Department of Nuclear Medicine,Chinese PLA General Hospital,Beijing 100853,China)
出处
《中华核医学与分子影像杂志》
CAS
北大核心
2020年第4期243-246,共4页
Chinese Journal of Nuclear Medicine and Molecular Imaging
基金
国家自然科学基金(81571715)。
