鼻塞式持续气道正压通气联合小剂量多巴胺治疗重症毛细支气管炎患儿的价值探讨

The Value of Nasal Continuous Positive Airway Pressure Ventilation Combined with Low Dose Dopamine in the Treatment of Children with Severe Bronchiolitis

目的分析鼻塞式持续气道正压通气联合小剂量多巴胺治疗重症毛细支气管炎的价值。方法在2018年1-12月方便选取该院接受诊疗的重症毛细支气管炎作为案例进行对比研究。共入选100例患儿,在患儿入选时以随机数字法方式处理分组。常规组提供面罩吸氧治疗,实验组采用鼻塞式持续气道正压通气联合小剂量多巴胺治疗措施。总结并对比两组患儿的临床治疗效果、症状消失时间以及药物相关并发症。结果实验组与常规组患儿的治疗总有效率分别为96.00%、82.00%,实验组患儿的临床治疗有效率相对于常规组患儿而言优势明显,组间对比差异有统计学意义(χ^2=11.214,P<0.05);实验组患儿的呼吸恢复正常、心率恢复正常、咳嗽消失、喘憋消失、啰音消失分别为(7.54±1.21)d、(5.13±2.01)d、(7.54±1.11)d、(5.12±1.46)d、(6.20±0.79)d,常规组患儿的呼吸恢复正常、心率恢复正常、咳嗽消失、喘憋消失、啰音消失分别为(9.21±1.65)d、(8.12±0.69)d、(10.23±3.11)d、(7.97±2.46)d、(9.79±1.44)d;实验组患儿的症状消失时间均显著短于常规组,组间对比差异有统计学意义(t=7.551、7.981、7.777、8.008、7.465,P<0.05)。实验组与常规组并发症发生率分别为4.00%、26.00%,实验组患儿的并发症发生率显著低于常规组患儿,组间对比差异有统计学意义(χ^2=12.013,P<0.05)。结论鼻塞式持续气道正压通气联合小剂量多巴胺治疗重症毛细支气管炎的价值突出,能够及时有效缓解患儿的临床症状,整体治疗安全性较高,值得推广应用。

Objective To analyze the value of nasal continuous positive airway pressure ventilation combined with low dose dopamine in the treatment of severe bronchiolitis.Methods From January to December 2018,severe bronchiolitis diagnosed and treated in the hospital was selected as a case study.Convenient selection of 100 children were selected and divided into groups by random number method when the children were selected.The routine group was treated with mask oxygen inhalation,and the experimental group was treated with nasal continuous positive airway pressure ventilation combined with low dose dopamine.The clinical therapeutic effect,symptom disappearance time and drug-related complications were summarized and compared between the two groups.Results The total effective rate of the experimental group and the routine group was 96.00%and 82.00%,respectively.The clinical effective rate of the experimental group was significantly higher than that of the routine group,and there was statistically significant difference between the two groups(χ^2=11.214,P<0.05).In the experimental group,the respiration returned to normal,the heart rate returned to normal,cough disappeared,wheezing disappeared,rale disappeared(7.54±1.21)d,(5.13±2.01)d,(7.54±1.11)d,(5.12±1.46)d,(6.20±0.79)d.In the routine group,the respiration returned to normal,the heart returned to normal,cough disappeared,wheezing disappeared,rale disappeared(9.21±1.65)d,(8.12±0.69)d,(10.23±3.11)d,(7.97±2.46)d,(9.79±1.44)d,The disappearance time of symptoms in the experimental group was significantly shorter than that in the routine group,and there was statistically significant difference between the two groups(t=7.551,7.981,7.777,8.008,7.465,P<0.05).The incidence of complications in the experimental group and the routine group was 4.00%and 26.00%,respectively.It was significantly lower than that in the routine group,and there was statistically significant difference between the two groups(χ^2=12.013,P<0.05).Conclusion Nasal continuous positive airway pressure ventilation combined with low dose dopamine is of great value in the treatment of severe bronchiolitis.It can relieve the clinical symptoms of children in time and effectively.The overall treatment is safe and worthy of popularization and application.