宫腔镜联合雌孕激素治疗人工流产术后宫腔粘连的临床效果评价

Clinical Evaluation of Hysteroscopy Combined with Estrogen and Progesterone in the Treatment of Intrauterine Adhesion after Artificial Abortion

目的总结并分析宫腔镜联合雌孕激素治疗人工流产术后宫腔粘连的临床效果。方法该文方便选取2017年4月-2019年3月该院收治的54例人工流产术后宫腔粘连患者,分为对照、观察两组。对照组采取雌孕激素人工周期治疗,观察组采用宫腔镜检查联合雌孕激素治疗。比较两组治疗3个月后宫腔粘连发生率、首次月经中期子宫内膜厚度以及治疗效果。结果治疗3个月后,观察组宫腔粘连发生率为7.41%(2/27),远低于对照组的29.63%(8/27),差异有统计学意义(χ^2=4.617,P<0.05);观察组治疗3个月后首次月经中期子宫内膜厚度为(3.52±1.61)mm,远小于对照组的(7.42±1.59)mm,差异有统计学意义(t=4.570,P<0.05);观察组治疗效果总有效率为96.30%(26/27),明显高于对照组的70.37%(19/27),差异有统计学意义(χ^2=4.800,P<0.05)。结论宫腔镜联合雌孕激素治疗人工流产术后宫腔粘连的临床效果显著,可明显降低患者宫腔粘连率,提高临床效果,值得推广。

Objective To summarize and analyze the clinical effects of hysteroscopy combined with estrogen and progesterone in the treatment of intrauterine adhesion after artificial abortion.Methods Convenient selection of 54 patients with intrauterine adhesions after induced abortion admitted to the hospital from April 2017 to March 2019 were selected and divided into control and observation groups.The control group was treated with estrogen and progesterone artificial cycle,while the observation group was treated with hysteroscopy combined with estrogen and progesterone.The incidence of intrauterine adhesions,the thickness of endometrium in the middle of the first menstruation and the therapeutic effect were compared between the two groups after 3 months of treatment.Results After 3 months of treatment,the incidence of intrauterine adhesions in the observation group was 7.41%(2/27),which was much lower than 29.63%(8/27)in the control group.The difference was statistically significant(χ^2=4.617,P<0.05);the first endometrial thickness of the observation group was(3.52±1.61)mm after 3 months of treatment,which was much smaller than that of the control group(7.42±1.59)mm and the difference was statistically significant(t=4.570,P<0.05).The total effective rate of the observation group was 96.30%(26/27),which was significantly higher than that of the control group(70.37%,19/27).The comparison between groups was statistically significant(χ^2=4.800,P<0.05).Conclusion The clinical effect of hysteroscopy combined with estrogen and progesterone in the treatment of intrauterine adhesion after artificial abortion is significant,which can significantly reduce the rate of intrauterine adhesions and improve the clinical effect.It is worthy of promotion.