痤疮丙酸杆菌的新命名及其与寻常痤疮的相关性

Propionibacterium acnes:renaming and its correlation with acne vulgaris

近来,有研究者建议将痤疮丙酸杆菌命名为Cutibacterium acnes(C.acnes),以更好研究其分型并与其他丙酸杆菌区分。C.acnes是人类皮肤重要的定植菌,参与维持皮肤健康,但也可能转变成为寻常痤疮的机会性病原菌。最新的研究显示,C.acnes不同型别间的平衡和与其他微生物的相互作用在寻常痤疮发生发展中发挥关键作用。本文综述C.acnes分型及其与寻常痤疮的相关性、药物敏感性和与其他微生物的相互作用。

Recently,biochemical and genomic studies have specified new classification methods and renamed Propionibacterium acnes as Cutibacterium acnes(C.acnes)to better study its phylotypes and distinguish it from other Propionibacterium species.C.acnes,an important commensal bacterium in human skin,is involved in maintaining skin health,and can also turn into an opportunistic pathogen causing acne vulgaris.Latest studies have showed that the balance between different phylotypes of C.acnes and its interaction with other microorganisms play a key role in the occurrence and development of acne vulgaris.This review summarizes correlations between C.acnes phylotypes and acne vulgaris,as well as antimicrobial susceptibility and interaction with other microorganism of C.acnes.