口腔癌术后患者症状群与生活质量的相关性研究

Correlation between symptom groups and quality of life in patients with oral cancer after surgery

目的:调查口腔癌患者治疗过程中的症状,探讨症状群种类及其与生活质量的相关性。方法:采用便利抽样法,选取某三级甲等医院口腔癌术后患者201例为研究对象,应用头颈癌安德森症状评估量表、华盛顿生活质量测评量表对其进行调查,分析二者相关性。结果:189例患者完成了问卷调查。口腔癌术后患者在疾病进展和治疗过程中存在多种症状,较严重的症状有吞咽咀嚼和发声讲话症状。探索性因子分析得出3个症状群,分别为口腔咽喉症状群、困倦-消化道症状群、疲劳-呼吸症状群。生存质量各维度得分及总分与3个症状群总分之间呈负相关(P<0.05)。结论:口腔癌患者在术后康复过程中存在影响生活质量的多个症状群,并且严重影响患者的生存质量。医护人员应把握这一特点,及时评估症状,积极管理症状群,提高患者的生存质量。

Objective To investigate the symptoms of patients with oral cancer during treatment,and explore the types of symptom groups and their correlation with quality of life.Methods Totally 201 patients with oral cancer after surgery were selected as the subject from a ClassⅢGrade A hospital using convenient sampling and investigated with the MD Anderson Symptom Inventory for Head and Neck cancer(MDASI-HN)and University of Washington Quality of Life Questionnaire(UW-QOL),and explore the relationship between them.Results Totally 189 patients completed the questionnaire.Patients with oral cancer showed many symptoms during the progression and treatment of the disease.Serious symptoms included swallowing,chewing and speaking.Exploratory factor analysis revealed three symptom groups,namely,oral and throat symptom group,drowsiness-digestive tract symptom group,and fatigue-respiratory symptom group.The scores of different dimensions and the total scores of quality of life were negatively correlated with the total scores of the three symptom groups(P<0.05).Conclusions There are multiple symptom groups in patients with oral cancer during postoperative rehabilitation,which seriously affect their quality of life.Medical workers should grasp this characteristic,evaluate symptoms in time,actively manage symptom groups,and improve the quality of life of patients.