虚拟认知康复训练在肝癌经肝动脉灌注化疗栓塞术致轻度认知障碍患者中的应用

Application of virtual cognitive rehabilitation training in patients with mild cognitive impairment induced by transcatheter arterial chemoembolization of liver neoplasms

目的观察虚拟认知康复训练在肝癌经肝动脉灌注化疗栓塞术(TACE)致轻度认知障碍患者健康教育中的应用价值。方法采用便利抽样法,选取2015年5月—2019年5月郑州大学第一附属医院收治的126例因TACE术致轻度认知障碍的肝癌患者,随机分为观察组和对照组,各63例。对照组予以常规认知干预,观察组实施虚拟认知康复训练,持续干预2个月。干预前后应用蒙特利尔认知评估量表(MoCA)、日常生活活动能力量表、中文版癌症自我管理效能量表(SUPPH)比较两组认知功能、日常生活能力及自我效能水平。结果干预前两组患者MoCA、ADL、SUPPH量表评分差异均无统计学意义(P>0.05)。干预2个月观察组患者MoCA量表总分(21.70±5.27)分、SUPPH量表总分(88.23±21.43)分,均高于对照组,差异有统计学意义(t值分别为2.949、4.509;P<0.05)。观察组干预后ADL量表(16.03±3.11)分,对照组(18.06±2.97)分,差异有统计学意义(t=3.747,P<0.05)。结论虚拟认知康复训练能改善因肝癌TACE术致轻度认知障碍者认知功能损伤,提升日常生活能力及自我效能水平。

Objective To observe the application value of virtual cognitive rehabilitation training in patients with mild cognitive impairment induced by transcatheter arterial chemoembolization(TACE)of liver neoplasms.Methods By the convenience sampling method,a total of 126 liver neoplasms patients with mild cognitive impairment induced by TACE who were admitted and treated in the First Affiliated Hospital of Zhengzhou University from May 2015 to May 2019 were selected.They were randomly divided into the observation group and the control group,with 63 cases in each group.The control group was given routine cognitive intervention while the observation group was given virtual cognitive rehabilitation training,and the intervention lasted for 2 months.Montreal Cognitive Assessment Scale(MoCA),Activities of Daily Living(ADL)Scale and Chinese version of Strategies Used by People to Promote Health(SUPPH)Scale were used to evaluate the cognitive function,ability of daily living and self-efficacy level of patients before and after intervention between two groups.Results There was no statistically significant difference in MoCA,ADL,and SUPPH scale scores of patients between the two groups before the intervention(P>0.05).After 2 months of intervention,the total score of the MoCA Scale(21.70±5.27)and the total score of the SUPPH Scale(88.23±21.43)in the observation group were higher than those in the control group,and the differences were statistically significant(t=2.949,4.509;P<0.05).After intervention,the score of the ADL Scale in the observation group was(16.03±3.11)and that in the control group was(18.06±2.97),and the difference was statistically significant(t=3.747,P<0.05).Conclusions Virtual cognitive rehabilitation training can improve the cognitive function of liver neoplasms patients with mild cognitive impairment caused by TACE and improve the activity of daily living and self-efficacy.