肿瘤营养治疗概述及其在卵巢癌中的应用

Overview of tumor nutrition therapy and its application in ovarian cancer

卵巢癌(OC)在妇科恶性肿瘤中死亡率最高,导致其死亡率最主要的三大问题中仅营养不良可通过规范化的营养治疗纠正。肿瘤营养治疗不仅为机体提供营养素及能量,更能发挥营养素的代谢及免疫调节功能。肿瘤营养疗法具有完整的理论体系,包括营养诊断(营养筛查、营养评估和综合评定)、营养干预(营养治疗五阶梯原则)及疗效评价3个阶段,贯穿于肿瘤治疗的全过程。手术、化疗、免疫治疗、分子靶向治疗以及终末期OC患者所适用的营养干预方式不尽相同。本文就肿瘤营养疗法及不同时期OC所适用的营养治疗方式进行概述,以期为OC的营养治疗提供参考。

Ovarian cancer(OC) has the highest mortality rate among gynecological malignancies, and of the three major causes of mortality, only malnutrition can be corrected with standardized nutritional therapy. Tumor nutrition therapy not only provides nutrients and energy for the body, but also plays an important role in nutrient metabolism and immune regulation. Tumor nutrition therapy has a complete theory system, including nutrition diagnosis(nutrition screening, nutrition evaluation and comprehensive evaluation), nutrition intervention(five steps of nutrition therapy) and efficacy evaluation, which runs through the whole process of tumor treatment. Surgery, chemotherapy, immunotherapy,molecular targeted therapy and end-stage with OC are different in terms of nutritional interventions. In this paper, the nutritional therapy for cancer and the nutritional therapy for OC in different stages are summarized in order to provide references for nutritional therapy for OC.