食物转换与早产儿智能发育的相关性

Correlation between food conversion and intelligence development in preterm infants

目的探索食物转换与早产儿智能发育的相关性。方法收集2017年1~6月广东省佛山市妇幼保健院出生,就诊时纠正月龄为18~24个月早产儿300例。采用回顾性调查询问早产儿食物转换等情况,并对研究对象行《儿童神经心理行为检查量表2016版》测评,使用多重线性回归对食物转换因素与大运动、精细运动、适应能力、语言、社交行为发育的相关性进行分析。结果未发现与大运动发育相关的食物转换因素;引入条块状食物时间与精细动作发育商(DQ)呈负相关(β=-0.549、P=0.023),引入蔬菜时间与适应能力DQ呈负相关(β=-0.820、P=0.005),引入辅食时间与语言DQ呈负相关(β=-1.319、P=0.047),引入辅食时间与社交行为DQ呈负相关(β=-1.827、P=0.001)。结论食物转换通过食物多样性、食物性状转换、喂食模式改变等影响早产儿精细动作、适应能力、语言、社交行为的发育,为临床改善早产儿的智能发育提供新思路。

Objective To explore the correlation between food conversion and intelligence development in preterm infants. Methods From January to June 2017, 300 cases with preterm infants who corrected aged 18-24 months were born in Foshan Women and Children Hospital of Guangdong Province were enrolled. A retrospective study was conducted to ask premature infants about food conversion, the subjects were evaluated with Children′s Neuropsychological Behavior Checklist 2016. Multiple linear regression was used to analyze the correlation between factors of food conversion and general movement development, fine motor, adaptability, language and social behavior. Results There was no correlations between food conversion factors and general movement development. There was a negative correlations between the introduction of block food time and the fine motor development quotient(β =-0.549, P = 0.023). There was a negative correlations between the time of vegetables introduction and adaptability DQ(β =-0.820, P = 0.005). There was a negative correlations between the time of complementary foods introduction and DQ of language(β =-1.319, P =0.047). There was a negative correlation between the complementary foods introduction time and social behavior DQ(β =-1.827, P = 0.001). Conclusion Food conversion affects the developments of fine motor, adaptability, language and social behavior of preterm infants via food diversity, food textures conversion and feeding mode change, so as to provide new ideas for clinical improvement of preterm infants′intelligent development.