经皮穴位电刺激治疗化疗后癌因性疲乏的临床效果

Clinical effect of transcutaneous electric acupoint stimulation in the treat-ment of cancer-related fatigue after chemotherapy

目的探讨经皮穴位电刺激治疗化疗后癌因性疲乏的临床效果。方法选取2018年10月~2019年6月于广东省中医院肿瘤科筛查符合标准的肿瘤患者116例,根据随机数字表法分为两组,每组各58例,研究脱落8例,最终对照组53例,试验组55例。对照组按肿瘤科常规诊疗护理,试验组在此基础上加用经皮穴位电刺激,选取中脘、气海、关元、双侧内关、双侧足三里和双侧三阴交穴,于化疗期间及化疗前后实施,20 min/次,1次/d,共治疗5 d。两组均治疗5 d,治疗前后采用Piper疲乏修订量表评分、癌症治疗功能评价一般量表(FACT-G)评分评价患者的疲乏状态和生活质量。结果两组治疗后Piper疲乏修订量表整体及各维度评分比较,差异有统计学意义(P <0.05)。对照组治疗后Piper疲乏修订量表整体及情感疲乏评分均高于治疗前,试验组治疗后Piper疲乏修订量表整体及各维度评分均低于治疗前,差异有统计学意义(P <0.05)。两组治疗后FACT-G总分及生理状况评分比较,差异有统计学意义(P <0.05)。试验组治疗后生理状况评分低于治疗前,功能状况评分高于治疗前;对照组治疗后FACT-G总分、生理状况评分均低于治疗前,功能状况评分高于治疗前,差异有统计学意义(P <0.05)。结论经皮穴位电刺激可缓解肿瘤患者的化疗后癌因性疲乏,并可改善肿瘤患者化疗后的生活质量。

Objective To investigate clinical effect of transcutaneous electric acupoint stimulation in the treatment of patients with cancer-related fatigue after chemotherapy.Methods Randomized study was used.From October 2018 to June 2019,116 cancer patients who met the standard were screened in Oncology Department of Guangdong Provincial Hospital of Traditional Chinese Medicine.According to the random number table method,they were divided into two groups,with 58 cases in each group,8 cases of abscission in each group,53 cases in final control group and 55 cases in final experimental group.Control group was given routine diagnosis and treatment nursing in Oncology Department,On this basis,experimental group was treated with transcutaneous acupoint electrical stimulation.■acupoints were selected.They were treated during and before chemotherapy,20 minutes one time,once a day,for 5 days.Treatment period of two groups was 5 days.The fatigue state and quality of life of the patients were evaluated by Piper fatigue revised scale and functional assessment of cancer therapy-general(FACT-G)scale before and after treatment.Results There were significant differences between two groups in scores of overall and all dimensions of Piper fatigue revised scale after treatment(P<0.05).In control group,overall scores and emotional fatigue score of Piper fatigue revised scale after treatment were higher than those before treatment,and in experimental group,overall score and all dimensions scores of Piper fatigue revised scale after treatment were lower than those before treatment,the differences were statistically significant(P<0.05).There were significant differences between two groups in total scores of FACT-G and physiological status scores after treatment(P<0.05).In experimental group,the score of physiological condition was lower than that before treatment,and the score of functional condition was higher than that before treatment;total score of FACT-G and the score of physiological status in control group were lower than those before treatment,and the score of functional status was higher than that before treatment,the differences were statistically significant(P<0.05).Conclusion Transcutaneous electric acupoint stimulation can alleviate cancer-related fatigue and improve the quality of life of tumor patients after chemotherapy.