烯丙雌醇与利托君联合应用于习惯性流产治疗中的效果评价

Evaluation of the Effect of Allylestradiol Combined with Ritodrine in the Treatment of Habitual Abortion

目的:探讨烯丙雌醇联合利托君对习惯性流产的治疗效果。方法:随机选取80例自2015年6月至2018年6月间被我院妇产科收治的习惯性流产患者,依据药物治疗方案均分至对照组与观察组。对照组用烯丙雌醇治疗,观察组加用利托君,比较药物治疗情况。结果:观察组的疾病治疗总有效率(95.0%)明显高于对照组的77.5%,所得数据间有统计学差异存在(P<0.05);观察组阴道出血、下腹疼痛和妊娠物排除缓解时间分别为(7.9±1.2)d、(7.2±0.6)d和(9.6±1.2)d,与对照组相比,存在统计学上的数据差异(P<0.05);(P<0.05);对照组和观察组患者在本次研究中有不良反应发生率上的统计学差异(P<0.05);两组患者存在生活质量上的统计学差异(P<0.05)。结论:烯丙雌醇联合利托君治疗习惯性流产效果明显,安全性高,也在缩短临床症状缓解时间和促进生活质量提升方面有着独特优势,有着深入探讨,推广应用的价值。

Objective: To investigate the therapeutic effect of allylestradiol combined with ritodrine on habitual abortion. Methods: 80 cases of habitual abortion were randomly selected from June 2015 to June 2018. They were divided into control group and observation group according to the drug treatment plan. The control group was treated with allylestradiol, while the observation group was treated with ritodrine to compare the drug treatment. Results: The total effective rate of treatment in the observation group(95.0%) was significantly higher than that in the control group(77.5%). There were statistical differences between the data obtained(P<0.05);the time of vaginal bleeding, lower abdominal pain and pregnancy relief in the observation group were(7.9±1.2)d,(7.2±0.6)d and(9.6±1.2)d, respectively, and there were statistical differences between the two groups(P<0.05);(P<0.05). There were statistical differences in the incidence of adverse reactions between the two groups in this study(P<0.05);there were statistical differences in the quality of life between the two groups(P<0.05). Conclusion: Allylestradiol combined with ritodrine in the treatment of habitual abortion has obvious effect and high safety. It also has unique advantages in shortening the time of clinical symptoms relief and promoting the quality of life. It has the value of in-depth discussion and application.