中西医结合治疗痰热型2型糖尿病临床观察

Clinical observation of Qingre Huatan Xiezhuo therapy on type 2 diabetes of phlegm-heat syndrome

目的:观察清热化痰泄浊法治疗痰热型2型糖尿病的疗效及作用机理。方法:将76例患者随机分成治疗组38例和对照组38例(脱落1例)。两组均予基础治疗(糖尿病教育、饮食、运动及常规降糖药)。治疗组在对照组的基础上内服加味柴胡温胆汤,同时联合针刺治疗,每周5次,共治疗12周。观察治疗前后中医证候评分及相关指标变化。结果:治疗组总有效率为84.21%,对照组总有效率为64.86%,两组比较有统计学意义(P﹤0.05)。结论:清热化痰泄浊法是治疗痰热型2型糖尿病的有效方法,其作用机制可能与改善胰岛素抵抗有关。

Objective:To observe the clinical effect and possible functional mechanism of Qingre Huatan Xiezhuo therapy on type 2 diabetes of phlegm-heat syndrome.Methods:76 cases of patients were randomly divided into treatment group(38 cases)and control group(38 cases with 1 case lost).Both groups were treated by basic therapy(diabetic education,diet and exercise,conventional hypoglycemic drugs).The treatment group was treated plus with Chaihu Wendan decoction on the basis of control group,at the same time combined with acupuncture(5 times a week,in total for 12 weeks).The changes of TCM symptom score and related indexes were observed before and after treatment.Results:Modified Chaihu Wendan decoction combined with acupuncture at acupoints of Taiyuan,Sanjia n,Jiexi,Fenglong,Quchi and Hegu,etc.could alleviate symptoms,and at the same time had better effects on lowering blood sugar and blood lipids and improving insulin resistance.Conclusion:Qingre Huatan Xiezhuo therapy is an effective therapy for treating type 2 diabetes of phlegm-heat syndrome,and its functional mechanism may be related to improving insulin resistance.