抑郁症状在社区老年糖尿病患者相关痛苦与衰弱状况间的中介效应

Mediating effect of depressive symptoms on diabetes-related distress and frailty in elderly patients with diabetes in the community

为探讨抑郁症状在社区老年糖尿病患者相关痛苦与衰弱状况间的中介作用,采用便利抽样法对衡阳市4个社区的343名60岁及以上的糖尿病患者进行调查。结果显示,社区老年糖尿病患者中衰弱和衰弱前期的发生率分别为26.5%和46.1%,抑郁症状的发生率为38.5%,糖尿病相关痛苦的发生率为56.6%;衰弱状况、抑郁症状及糖尿病相关痛苦间存在相关性;调整混杂因素后,单独存在糖尿病相关痛苦、单独存在抑郁症状、同时有抑郁症状和糖尿病相关痛苦的患者发生衰弱和衰弱前期的风险均显著增高;抑郁症状在糖尿病相关痛苦与衰弱状况间发挥部分中介效应,中介效应与总效应之比为44.4%。结果说明,社区老年糖尿病患者衰弱、抑郁症状及糖尿病相关痛苦的发生率高,抑郁症状在糖尿病相关痛苦与衰弱状况间发挥部分中介效应。

To explore the mediating effects of depressive symptoms on diabetes-related distress and frailty in elderly patients with diabetes in the community,a total of 343 diabetic patients aged 60 years or older in four communities in Hengyang City was surveyed using a convenient sampling method.Results showed that the prevalence of frailty and prefrailty in the subjects were 26.5%and 46.1%,38.5%had depressive symptoms,and 56.6%had diabetes-related distress.There is a correlation between frailty,depressive symptoms and diabetes-related distress.After adjustment for confounding factors,patients with diabetes-related distress alone,depressive symptoms alone,both depressive symptoms and diabetes-related distress were at higher risk of frailty and prefrailty,depressive symptoms play a partial mediating effect between diabetes-related distress and frailty,and the ratio of mediating effect to total effect is 44.4%.The incidence of frailty and negative emotions such as depressive symptoms and diabetes-related distress in elderly patients with diabetes in the community is high,and depressive symptoms play a partial mediating effect between diabetes-related distress and frailty.