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阿托伐他汀联合苯磺酸氨氯地平治疗高血压并原发性高血脂的临床应用效果观察 被引量:6

Clinical Effect of Atorvastatin Combined with Amlodipine Besylate in the Treatment of Hypertension with Essential Hyperlipidemia
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摘要 目的:分析和探讨阿托伐他汀联合苯磺酸氨氯地平治疗高血压并原发性高血脂的临床应用效果。方法:选择我院(2018年1月至2019年1月)高血压并原发性高血脂患者(66例)作为研究对象,并采用"随机数字表法"分为对照组(33例)和观察组(33例),对照组患者采用苯磺酸氨氯地平治疗,观察组患者在对照组患者的基础上加用阿托伐他汀治疗,对比两组患者的治疗效果。结.果:观察组患者的收缩压和舒张压均低于对照组,左心室容积指数高于对照组;总胆固醇、甘油三酯以及低密度脂蛋白均低于对照组(P值<005)。结论:阿托伐他汀联合苯磺酸氨氯地平治疗高血压并原发性高血脂的临床应用效果显著,不仅能够有效地改善患者的血压水平,还能够显著改善患者的血脂水平,适合在临床进行开展和普及。 Objective: To analyze and explore the clinical application of atorvastatin combined with amlodipine besylate in the treatment of hypertension and primary hyperlipidemia. Methods: Patients with hypertension and primary hyperlipidemia(66 cases) from our hospital(January 2018 to January 2019) were selected as the research subjects, and the "random number table method" was used to divide the control group(33 cases) and In the observation group(33 cases), the patients in the control group were treated with amlodipine besylate. The patients in the observation group were treated with atorvastatin on the basis of the patients in the control group. The treatment effects of the two groups were compared. Results: The systolic and diastolic blood pressure of the observation group were lower than those of the control group, and the left ventricular volume index was higher than that of the control group. The total cholesterol, triglycerides, and low density lipoprotein were lower than those of the control group(P<0.05). Conclusion: Atorvastatin combined with amlodipine besylate in the treatment of hypertension and primary hyperlipidemia has a significant clinical effect. It can not only effectively improve the blood pressure level of patients, but also significantly improve the blood lipid level of patients. It is suitable for clinical use. Carry out and spread.
作者 黄丹 雷刚 汪星 叶晓娟 张水杰 陈桂欣 曾敏灵 HUANG Dan;LEI Gang;WANG Xing;YE Xiao-juan;ZHANG Shui-jie;CHEN Gui-xin;ZENG Min-ling(Department of Neurology,Tianyou Hospital Affiliated to Wuhan University of science and technology,Wuhan Hubei 430064,China)
出处 《药品评价》 CAS 2020年第3期67-68,共2页 Drug Evaluation
关键词 阿托伐他汀 苯磺酸氨氯地平 高血压并原发性高血脂 应用效果 Atorvastatin Amlodipine Hypertension with Primary Hyperlipidemia Application Effect
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