依达拉奉联合氯吡格雷治疗急性脑梗死的护理研究

Nursing Study of Edaravone Combined with Clopidogrel in the Treatment of Acute Cerebral Infarction

目的:探讨依达拉奉联合氯吡格雷治疗急性脑梗死的护理研究。方法:选择2017年1月至2018年12月治疗的急性脑梗死患者82例作为对象,随机数字表分为对照组(n=41)和观察组(n=41)。对照组患者给予依达拉奉治疗,观察组患者给予依达拉奉联合氯吡格雷治疗,再给予护理干预,比较两组患者的护理后神经系统缺损程度、不良反应发生率、恢复效果情况。结果:两组患者治疗前神经系统缺损程度评分均无统计学意义(P>0.05);观察组患者治疗后1个月、2个月、3个月的神经系统缺损程度评分均低于对照组(P<0.05);两组患者不良反应率均无统计学意义(P>0.05),观察组的不良反应低于对照组(P<0.05);观察组经治疗及护理后血清值恢复正常时间、恢复自主活动时间、住院时间均短于对照组,观察组患者的生活质量评分高于对照组(P<0.05)。结论:依达拉奉联合氯吡格雷治疗急性脑梗死可有效清除自由基,改善神经系统缺损程度,药物安全性高,有效的护理可以提高治愈率、缩短患者的康复时间,值得推广与应用。

Objective:To explore the nursing study of edaravone combined with clopidogrel in the treatment of acute cerebral infarction.Methods:82 patients with acute cerebral infarction treated from January 2017 to December 2018 were selected as objects,and the random number table was divided into the control group(n=41)and the observation group(n=41).Patients in the control group were treated with edaravone,while patients in the observation group were treated with edaravone combined with clopidogrel,followed by nursing intervention.The degree of neurological defects,incidence of adverse reactions and recovery effect of patients in the two groups were compared.Results:There was no statistical significance in the scores of neurological defects before treatment in the two groups(P>0.05).The scores of neurological defects in the observation group at 1 month,2 months and 3 months after treatment were lower than those in the control group(P<0.05).The rate of adverse reactions in the two groups was not statistically significant(P>0.05),and the adverse reactions in the observation group were lower than those in the control group(P<0.05).After treatment and nursing,serum values of the observation group returned to normal time,time to restore independent activity,hospital stay were shorter than the control group,and the quality of life score of the observation group was higher than the control group(P<0.05).Conclusion:Edaravone combined with clopidogrel in the treatment of acute cerebral infarction can effectively remove free radicals,improve the degree of neurological defects,high drug safety,effective nursing can improve the cure rate,shorten the recovery time of patients,it is worthy of promotion and application.