合理用药有效干预对药品不良反应发生率的影响

Effect of Effective Intervention of Clinical Pharmacists through Reasonable Drug Use on Incidence of Adverse Drug Reaction

目的探究临床药师通过合理用药有效干预对药品不良反应发生率的影响。方法选取2015年8月—2016年8月医院收治通过临床药师合理用药有效干预前的不同患病原因用药患者,作为对照组。选取2016年9月—2017年8月医院收治通过临床药师合理用药有效干预后的不同患病原因用药患者,作为研究组。两组研究患者各45例。比较两组患者经过治疗后不良反应的发生情况对比,两组患者干预前后治疗效果对比,以及对不同药品种类分布研究对比。结果研究组患者经过合理用药有效干预后针对各类药品不良反应发生情况显著少于对照组患者(P<0.05)。研究组患者经过合理用药有效干预后生活质量情况显著优于对照组患者(P<0.05)。研究组患者经过合理用药有效干预后治疗情况显著优于对照组患者(P<0.05)。结论治疗过程当中,临床药师通过合理用药有效干预针对各类药品不良反应发生率显著减少,治疗的有效性明显提高,生活质量情况显著提高在临床上具有更加积极地作用。

Objective To investigate the effect of effective intervention of clinical pharmacists on the incidence of adverse drug reactions.Methods From August 2015 to August 2016,patients with different causes were treated by clinical pharmacists before effective intervention.From September 2016 to August 2017,patients with different causes of illness who have been effectively interfered with by clinical pharmacists were selected as a research group.There were 45 cases in each group.We compared the occurrence of adverse reactions after treatment between two groups,the effect of treatment before and after intervention,and the distribution of different drugs.Results The incidence of adverse drug reactions was significantly lower in the study group after effective intervention(P<0.05).The quality of life of the patients in the study group was significantly better than that of the control group(P<0.05).The patients in the study group were treated better than control group’s patients after effective intervention(P<0.05).Conclusion In the course of treatment,the effective intervention of clinical pharmacists against all kinds of drugs by rational drug use has significantly reduced the incidence of adverse reactions,the effectiveness of treatment has obviously improved,and the quality of life has significantly improved.It has a more positive role in clinic.