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全脑放疗联合替莫唑胺化疗对脑转移肿瘤的疗效及安全性分析

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摘要 目的探究脑转移肿瘤患者采取全脑放疗联合替莫唑胺化疗治疗疗效及安全性。方法探讨2015年8月~2016年8月于赤峰学院附属医院收治的120例脑肿瘤转移患者为研究对象,按照随机方式将其分成对照组和实验组,各60例。对照组实施全脑放射治疗,实验组采取全脑放疗联合替莫唑胺化疗治疗,对比分析两组患者的不良反应、生存时间、近期疗效等。结果实验组近期有效率达96.7%显著优于对照组71.7%,差异具有统计学意义(x^2=15.347,P<0.05);两组患者的不良反应发生率经对比显示,两组差异无统计学意义(x^2=1.237,P>0.05);观察组患者的无进展生存时间和中位生存时间与对照组相比均略高,且差异较为显著(t=6.023、18.634,P<0.05)。结论脑转移肿瘤患者进行全脑放疗联合替莫唑胺治疗效果较为显著,延长生存期限,提高生存质量,不良反应发生率较低,耐受性强,较为安全,值得临床应用。
出处 《中华养生保健》 2020年第6期128-129,共2页 CHINESE HEALTH CARE
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