新型冠状病毒感染的肺炎发病机制和治疗策略:肺癌免疫检查点抑制剂相关不良事件的启发

Pathogenesis and treatment strategies of novel coronavirus pneumonia:Reflections on immune checkpoint inhibitor-related adverse events in lung cancer

2019年12月以来,中国武汉陆续发现了多例新型冠状病毒感染的肺炎患者,其影像学表现与肺癌免疫检查点抑制剂(immune checkpoint inhibitors,ICI)相关肺炎相似,因此推测它们可能有相似的发病机制和治疗策略。在此予以综述,供抗疫前线专家组参考,以利于降低病死率。

In December 2019,an outbreak of pneumonia associated with the coronavirus disease 2019(COVID-19)occurred in Wuhan,China.The lung imaging finding is like that of the lung cancer immune checkpoint inhibitors(ICI)associated pneumonia.Therefore,we speculated that they may have similar pathogenesis and treatment strategies,which is reviewed in this article in order to provide some reference to timely and effectively reduce the fatality rate of COVID-19.