间充质干细胞治疗糖尿病足的研究进展

Research advances in mesenchymal stem cells in treatment of diabetic foot

糖尿病足(diabetic foot,DF)是糖尿病常见的慢性并发症之一,其继发感染是非外伤性截肢的主要原因。DF严重影响糖尿病患者的生活质量,并且给家庭及社会带来严重的经济负担。间充质干细胞(mesenchymal stem cells,MSCs)能有效促进新血管生成,促进创面愈合,是治疗糖尿病足的新方法。本文对MSCs治疗DF的研究进展进行综述,从而为临床治疗糖尿病足提供理论依据。

Diabetic foot(DF)is one of the most common chronic complications of diabetes and its secondary infection is the major cause of non-traumatic amputation,which greatly affects the quality of life of diabetic patients and brings serious economic burdens to families and the society.Mesenchymal stem cell(MSCs)treatment can effectively promote angiogenesis and wound healing and is thus a new method for the treatment of DF.This article reviews the research advances in MSCs in the treatment of DF,in order to provide a theoretical basis for the clinical treatment of DF.