人巨细胞病毒感染与新生儿病理性黄疸

The Correlations Between Human Cytomegalovirus Infection and Neonatal Pathological Jaundice

对人巨细胞病毒(human cytomegalovirus,HCMV)感染与新生儿病理性黄疸的相关问题进行系统综述,并指出对出生24小时之内出现黄疸的患儿尤其要高度怀疑HCMV感染,有必要常规进行病毒检测筛查;可采集患儿晨尿作为检测标本替代血液监测,且需反复、连续、多次检查,以提高检出率;若条件允许,同时采集产妇的乳汁进行HCMV核酸检测;发挥现代中医治疗疾病的特色与优势,推进中西医结合治疗在新生儿黄疸中的广泛应用,并加强产前及围生期HCMV感染筛查,强调预防工作,以降低感染风险。

In the paper,the related problems about the correlation between human cytomegalovirus(HCMV)infection and neonatal infection were summarized systematically,it′s necessary to perform viral detection and screening as routine,especially when jaundice was manifested within 24 hours after the birth in the baby,and HCMV infection should be suspected highly;urina sanguinis could be collected as the samples to replace blood monitoring,and serial detection should be repeated for many times to raise the detection rate;if the conditions allowed,the puerperant’s milk should be collected to detect HCMV nuclein;in order to reduce the infection risk,the characteristics and advantages of modern TCM in the treatment for the disease should be developed,the application of integrative medicine therapy to neonatal jaundice should be promoted,HCMV infection during antepartum and perinatal period should be enhanced,as well as the prevention work.