济南市10例儿童新型冠状病毒肺炎确诊病例流行病学和临床特征

Epidemiological and clinical characteristics of 10 children with coronavirus disease(COVID-19)in Jinan City

目的回顾性分析济南市报告的10例儿童新型冠状病毒肺炎确诊病例的流行病学和临床特征。方法依据《新型冠状病毒肺炎诊疗方案(试行第5版)》中新型冠状病毒肺炎诊断标准和临床分型,以济南市截至2020年2月26日报告的所有儿童(年龄<18岁)新型冠状病毒肺炎确诊病例为研究对象,收集儿童确诊病例的流行病学和临床资料,对儿童确诊病例的人口学、流行病学、临床特征进行描述性分析。结果济南市共报告儿童新型冠状病毒肺炎确诊病例10例,男性3例,女性7例。年龄分布包括婴幼儿、学龄前儿童和学龄儿童。10例儿童确诊病例均为家庭内传播病例,在对确诊病例密切接触者主动筛查中发现,父母是其主要的传染来源。患儿发病至确诊的时间间隔最短为0 d,最长为6 d,时间间隔中位数为1.5 d。儿童确诊病例的临床症状为轻型3例和普通型7例,5例患儿首次检出新型冠状病毒核酸阳性时身体无不适症状。截至2月26日,10例儿童COVID-19确诊病例中有6例患儿出院,住院天数中位数为15 d。结论儿童新型冠状病毒肺炎确诊病例以家庭内感染为主,开展密切接触者集中隔离医学观察和主动采样监测对病例的早发现有重要意义。

Objective To analysis the epidemiological and clinical characteristics of 10 children with coronavirus disease(COVID-19)in Jinan City.Methods To collect the information of all the children(<18 years)with COVID-19 in Jinan City by Feb 26,2020.The diagnosis was based on China’s"COVID-19 diagnosis and treatment plan(fifth version)".Data of general information,epidemiological and clinical characteristics were analyzed.Results Ten children with COVID-19 were reported,including 3 males and 7 females.Age distribution included all stages of children.All the 10 confirmed cases of children were family transmitted cases.Parents were the main source of infection in the active sampling and monitoring of close contacts.The shortest time interval from onset to diagnosis was 0 days,the longest was 6 days,and the median time interval was 1.5 days.The clinical symptoms of COVID-19 were mild(3 cases)and common(7 cases).Five children had no symptoms when they were detected the new coronavirus nucleic acid positive for the first time.As of Feb 26,6 of the 10 confirmed cases were discharged,with a median length of stay was 15 days.Conclusion Family infection is the main source of infection for children.It is important to carry out centralized isolation medical observation and active sampling monitoring of close contacts for early detection of cases.