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包覆花色苷W1/O/W2型乳液的消化特性及其缓释效果 被引量:6

Digestion Properties and Controlled Release of Anthocyanins-Loaded Water-in-Oil-in-Water Double Emulsions Stabilized by Polyglycerol Polyricinoleate and Casein Sodium
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摘要 研究体外消化对包埋葡萄皮花色苷(anthocyanins,ACNs)W1/O/W2型乳液控释和抗氧化性能的影响。W1/O/W2型乳液粒径约为(149.33±1.44)nm,并且呈双峰分布,ACNs的包封率为(82.99±2.38)%。体外口腔消化对W1/O/W2型乳液液滴结构无明显影响。经口进入模拟胃消化后,W1/O/W2型乳液因蛋白质水解失去双层结构,释放的W1/O液滴聚集在一起而使粒径显著增加(P<0.05)。经胃进入模拟肠道消化后,W1/O液滴破碎,平均粒径(d<150 nm)显著减小(P<0.05),此时具有最高的抗氧化活性。结果表明,W1/O/W2型乳液能有效地保护ACNs免受体外口腔和胃消化的影响,并可靶向地在模拟小肠内传递和释放。 The effects of in vitro gastrointestinal digestion on the controlled release and antioxidant properties of encapsulated grape skin anthocyanins(ACNs)from water-in-oil-in-water(W1/O/W2)double emulsions were determined.The double emulsions exhibited a bimodal distribution(d=(149.33±1.44)nm)with an encapsulation efficiency of(82.99±2.38)%.Oral digestion in vitro did not affect the structure of the emulsion droplets.After simulated gastric digestion,the double W1/O/W2 emulsions became a single W1/O emulsion due to proteolysis,and the released emulsion droplets were aggregated together leading to a significant increase(P<0.05)in average droplet size.During subsequent intestinal digestion,the W1/O droplets were broken,so that the average droplet size(d<150 nm)decreased significantly(P<0.05),and the highest antioxidant activities were identified.Our results indicated that the encapsulated ACNs were effectively protected by the W1/O/W2 double emulsions against in vitro oral and gastric digestion,and were delivered to the target in the simulated small intestine.
作者 徐伟丽 张玉琪 朱元昊 鲁兆新 XU Weili;ZHANG Yuqi;ZHU Yuanhao;LU Zhaoxin(School of Chemistry and Chemical Engineering,Harbin Institute of Technology,Harbin 150001,China)
出处 《食品科学》 EI CAS CSCD 北大核心 2020年第10期1-7,共7页 Food Science
基金 国家自然科学基金青年科学基金项目(31501481)。
关键词 花色苷 W1/O/W2型乳液 控制释放 体外消化 酪蛋白钠 anthocyanins W1/O/W2 double emulsions controlled release in vitro digestion casein sodium
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