阿昔洛韦抗病毒治疗对传染性单核细胞增多症 (IM) 患儿发热持续时间、住院时间的影响

Effect of Acyclovir Antiviral Therapy on Fever Duration and Hospitalization Time in Infectious Monocytosis (IM) Children

目的:研究探讨阿昔洛韦抗病毒治疗对于儿童传染性单核细胞增多症的发热持续时间以及住院时间的影响。方法:选取某院2017年10月~2018年10月收治的38例传染性单核细胞增多症的患儿(IM),随机分为观察组与对照组,每组19例。对照组患儿应用对症治疗等常规治疗的方法,观察组患儿在常规治疗的基础上应用阿昔洛韦治疗。治疗结束后,比较两组患儿的临床治疗效果、38.1℃~39℃以及39.1℃~40℃两个阶段的发热持续时间以及住院时间。结果:观察组患儿的治疗效果显著高于对照组患儿,观察组患儿的在38.1℃~39℃以及39.1℃~40℃两个阶段的发热持续时间以及住院时间等显著短于对照组患儿,差异均具有统计学意义(P<0.05)。结论:阿昔洛韦抗病毒治疗可以显著提高传染性单核细胞增多症患儿的治疗效果,缩短患儿的发热时间以及减少住院时间。

Objective:To study the effect of acyclovir antiviral therapy on the duration of fever and hospitalization in children with infectious mononucleosis. Methods:38 children with infectious mononucleosis(IM) admitted to a hospital from October 2017 to October 2018 were randomly divided into observation group and control group, 19 cases in each group. The control group was treated with symptomatic treatment and other routine treatment methods, while the observation group was treated with acyclovir on the basis of routine treatment. After treatment, the clinical efficacy, duration of fever and hospitalization time of 38.1 to 39 degrees and 39.1 to 40 degrees were compared between the two groups. Results: The treatment effect of the observation group was significantly higher than that of the control group. The duration of fever and hospitalization in the observation group were significantly shorter than those in the control group at 38.1 to 39 degrees and 39.1 to 40 degrees(P<0.05). Conclusion:Acyclovir antiviral therapy can significantly improve the therapeutic effect of infectious mononucleosis in children, shorten the fever time and reduce hospitalization time.