酸枣仁汤加减治疗顽固性失眠临床观察

Clinical Observation of Modified Suanzaoren Decoction in the Treatment of Intractable Insomnia

目的:分析顽固性失眠患者应用酸枣仁汤加减治疗的临床疗效。方法:选取96例顽固性失眠患者随机分为对照组、研究组,各48例。对照组用基础西医治疗,研究组在对照组基础上增加酸枣仁汤加减治疗。比较治疗前后不同组别睡眠情况,治疗效果,副作用。结果:治疗前两组睡眠质量、入睡时间、睡眠时间、睡眠效率、总分分数差异不明显(P>0.05),治疗后均明显降低(P<0.05),研究组明显低于对照组(P<0.05);研究组治疗总有效率明显高于对照组(P<0.05);两组副作用发生率差异不明显(P>0.05)。结论:顽固性失眠患者应用酸枣仁汤加减治疗可改善睡眠情况、治疗效果,且不会导致副作用的明显增多。

Objective:To analyze the clinical effect of the treatment of intractable insomnia patients with the addition and subtraction of Suanzaoren decoction.Methods:96 patients with refractory insomnia were randomly divided into a control group and a research group,48 cases each.The control group was treated with basic western medicine,and the research group increased the addition and subtraction of Suanzaoren decoction on the basis of the control group.Compare sleep conditions,treatment effects and side effects of different groups before and after treatment.Results:There was no significant difference in sleep quality,time to fall asleep,sleep time,sleep efficiency,and total score before treatment(P>0.05),and it was significantly reduced after treatment(P<0.05).The study group was significantly lower than the control group(P<0.05).The total effective rate of treatment in the study group was significantly higher than that in the control group(P<0.05).There was no significant difference in the incidence of side effects between the two groups(P>0.05).Conclusion:The application of Suanzaoren decoction in patients with refractory insomnia can improve sleep conditions and therapeutic effects without causing significant increase of side effects.