麻杏石甘汤联合头孢克肟对肺炎患儿有效性及免疫球蛋白水平的影响

A Study on Effectiveness of Maxing Shigan Tang Combined with Cefixime in Treating Children with Pneumonia and Its Effect on Immunoglobulin Levels

目的:探讨麻杏石甘汤联合头孢克肟对肺炎患儿有效性及免疫球蛋白水平的影响。方法:将肺炎患儿116例作为研究对象,根据治疗方式的不同随机分为2组各58例,对照组采用头孢克肟进行治疗,研究组在使用头孢克肟治疗的同时采用麻杏石甘汤进行治疗。对比2组患者的疗效、免疫球蛋白水平、不良反应以及炎症因子水平。结果:研究组总有效率为98.3%,对照组为89.7%,2组比较,差异有统计学意义(P<0.05)。治疗前,2组免疫球蛋白水平比较,差异无统计学意义(P>0.05)。治疗后,2组免疫球蛋白水平均较前改善(P<0.05);研究组IgG、IgM、IgA等水平均高于对照组(P<0.05)。治疗前,2组炎症因子比较,差异无统计学意义(P>0.05)。治疗后,研究组血清C-反应蛋白(CRP)、白细胞介素-6 (IL-6)以及肿瘤坏死因子-α(TNF-α)水平低于对照组(P<0.05)。研究组不良反应发生率低于对照组(P<0.05)。结论:采用麻杏石甘汤联合头孢克肟治疗肺炎患儿,临床疗效确切,可加强免疫力,降低机体炎症因子水平,并发症少。

Objective: To discuss the effectiveness of Maxing Shigan tang combined with cefixime in treating children with pneumonia and its effect on immunoglobulin levels. Methods: A total of 116 cases of children with pneumonia were selected as the study subjects and randomly divided into two groups according to different treatment methods,58 cases in each group. The control group was treated with cefixime,and the study group was additionally treated with Maxing Shigan tang based on the treatment of the control group. The curative effect,immunoglobulin levels,adverse reactions and levels of inflammatory factors in the two groups were compared. Results:The total effective rate was 98.3% in the study group and89.7% in the control group,the difference being significant(P<0.05). Before treatment,there was no significant difference being found in the comparison of immunoglobulin levels between the two groups(P>0.05). After treatment, the immunoglobulin levels in the two groups were improved when compared with those before treatment(P<0.05);the levels of IgG,IgM and IgA in the study group were higher than those in the control group(P<0.05). Before treatment,there was no significant difference being found in the comparison of levels of inflammatory factors between the two groups(P>0.05). After treatment,the levels of C-reactive protein(CRP),interleukin-6(IL-6) and tumor necrosis factor-α(TNF-α) in serum in the study group were lower than those in the control group(P<0.05). The incidence of adverse reactions in the study group was lower than that in the control group(P<0.05). Conclusion: The therapy of Maxing Shigan tang combined with cefixime in treating children with pneumonia has definite curative effect, which can strengthen immunity and reduce levels of inflammatory factors with few complications.