清解汤治疗儿童急性荨麻疹临床研究

Clinical Study on Qingjie Tang for Acute Urticaria in Children

目的:观察清解汤治疗儿童急性荨麻疹(AU)的临床疗效及安全性。方法:选取60例急性荨麻疹患儿,按随机数字表法分为对照组和研究组各30例,对照组采用氯雷他定颗粒治疗,研究组采用清解汤治疗。观察比较2组的临床疗效、症状积分、不良反应发生率。结果:研究组临床总有效率为90.00%,对照组为80.00%,2组比较,差异无统计学意义(P>0.05)。治疗前,2组症状积分比较,差异无统计学意义(P>0.05)。治疗后,2组瘙痒、风团、水肿、皮损等症状积分较治疗前降低(P<0.05),且研究组的瘙痒、风团、水肿、皮损等症状积分均低于对照组(P<0.05)。研究组不良反应发生率为6.67%,低于对照组36.67%,差异有统计学意义(P<0.05)。结论:清解汤治疗儿童AU能有效改善患儿的症状积分,提高临床疗效,降低不良反应的发生,促进患儿恢复。

Objective:To observe the clinical effect of Qingjie tang for acute urticaria(AU)in children and its safety.Methods:A total of 60 cases of AU children were divided into the control group and the study group according to the random number table method,30 cases in each group.The control group was treated with loratadine granules,and the study group was treated with Qingjie tang.The clinical effect,the symptom scores and the incidence of adverse reactions in the two groups were observed and compared.Results:The total clinical effective rate was 90.00%in the study group and 80.00%in the control group,there being no significance in the difference(P>0.05).Before treatment,there was no significant difference being found in the comparison of the symptom scores between the two groups(P>0.05).After treatment,the scores of pruritus,wheal,edema and skin lesions in the two groups were decreased when compared with those before treatment(P<0.05),and the above symptom scores in the study group were lower than those in the control group(P<0.05).The incidence of adverse reactions was 6.67%in the study group,lower than that of 36.67%in the control group,the difference being significant(P<0.05).Conclusion:Qingjie tang in treating children with AU can effectively improve the symptom scores and clinical effect,reduce the incidence of adverse reactions and promote the recovery of children.