谷红注射液穴位注射联合常规疗法治疗糖尿病周围神经病变临床研究

Clinical Study on Point Injection with Guhong Injection Combined with Routine Therapy for Diabetic Peripheral Neuropathy

目的:观察谷红注射液穴位注射辅助治疗糖尿病周围神经病变(DPN)的疗效。方法:将108例糖尿病周围神经病变瘀血阻络证患者随机分为对照组和观察组各54例。2组均严格控制血糖,予甲钴胺注射液、硫辛酸胶囊治疗,并给予相应护理措施,观察组加予谷红注射液穴位注射,疗程均为4周。治疗前后评定多伦多临床评分系统(TCSS)评分和瘀血阻络证评分,比较2组的临床疗效。结果:治疗后,观察组临床疗效优于对照组(P<0.05)。2组四肢疼痛、感觉减退、肢软麻木、四肢发凉4项症状评分与总分均较治疗前下降(P<0.01);观察组4项主要症状评分及总分均低于对照组(P<0.01)。2组TCSS症状、反射、感觉试验评分及总分均较治疗前下降(P<0.01),观察组3项维度评分及总分均低于对照组(P<0.01)。结论:在常规西药治疗基础上给予谷红注射液穴位注射,可有效改善DPN的临床症状,改善神经功能,提高临床疗效。

Objective:To observe the curative effect of point injection with Guhong injection combined with routine therapy for diabetic peripheral neuropathy.Methods:A total of 108 cases of patients with diabetic peripheral neuropathy with blood stasis obstructing the collateral syndrome were randomly divided into the control group and the observation group,54 cases in each group.Both groups received strict control of blood glucose,treatment with mecobalamin injection and lipoic acid capsules,and corresponding nursing measures.The observation group was additionally given point injection with Guhong injection.Both groups were treated for four weeks.Before and after treatment,the scores of Toronto Clinical Scoring System(TCSS)and blood stasis obstructing the collateral syndrome were evaluated.The clinical effect in the two groups was compared.Results:After treatment,the clinical effect in the observation group was better than that in the control group(P<0.05).The scores of hypoesthesia and the pain,weakness,numbness and coldness in limbs and their total scores in the two groups were decreased when compared with those before treatment(P<0.01).The scores of the four main symptoms and their total score in the observation group were all lower than those in the control group(P<0.01).The total scores of TCSS and the TCSS test scores of symptoms,reflections and sensory in the two groups were decreased when compared with those before treatment(P<0.01).The three-dimension scores in TCSS and their total score in the observation group were all lower than those in the control group(P<0.01).Conclusion:Based on routine western medicine,point injection with Guhong injection can effectively reduce the clinical symptoms of DPN,and improve nerve function and clinical effect.