奥美拉唑,阿莫西林,克拉霉素三联疗法治疗胃溃疡的临床疗效

The Clinical Effect of Omeprazole, Amoxillin and Claymycin in the Treatment of Gastric Ulcer

目的研究分析奥美拉唑、阿莫西林以及克拉霉素三联疗法治疗胃溃疡的临床疗效。方法选取2017年4月至2018年5月间在我院接受治疗的60例胃溃疡患者为研究样本,随机将其分为实验组与对照组各30例,对照组患者接受西咪替丁联合阿莫西林治疗,实验组患者接受奥美拉唑、阿莫西林以及克拉霉素三联疗法治疗。比较两组患者的临床治疗效果、治疗期间不良反应发生情况以及胃溃疡症状消失时间。结果实验组患者的治疗总有效率为93.33%、不良反应发生率为3.33%、胃溃疡症状消失时间为(4.27±0.81)d,均显著优于对照组且差异均有统计学意义(P<0.05)。结论对胃溃疡患者采用奥美拉唑、阿莫西林以及克拉霉素三联疗法治疗胃溃疡,临床治疗有效率与安全性较高,症状缓解所需时间较短,具有较高的临床推广价值。

Objective To study the clinical efficacy of omeprazole,amoxicillin and clarithromycin in the treatment of gastric ulcer.Methods 60 patients with gastric ulcer treated in our hospital from April 2017 to May 2018 were randomly divided into experimental group(n=30)and control group(n=30).The patients in control group were treated with cimetidine combined with amoxicillin,and the patients in control group were treated with cimetidine combined with amoxicillin.The experimental group received omeprazole,amoxicillin and clarithromycin triple therapy.The clinical effects,adverse reactions and gastric ulcer symptoms were compared between the two groups.Results Treatment of patients in experimental group The total effective rate of the treatment was 93.33%,the incidence of adverse reaction was 3.33%,and the disappearance time of the symptom of the gastric ulcer was(4.27±0.81)d,which was significantly better than that of the control group(P<0.05).Conclusion The treatment of the stomach ulceration with the triple therapy of Ameiraqi,amoxicillin and clarithromycin in the patients with the stomach ulceration has the advantages of high effective rate and safety,short time for clinical remission,and high clinical popularization value.