前列舒通胶囊联合前列康灌肠汤对湿热瘀阻型Ⅲ型慢性前列腺炎患者的临床疗效

Clinical effects of Qianlie Shutong Capsules combined with Qianliekang Decoction Enema on patients with typeⅢchronic prostatitis due to Damp heat and Blood stasis Accumulation

目的 观察前列舒通胶囊联合前列康灌肠汤对湿热瘀阻型Ⅲ型慢性前列腺炎患者的临床疗效.方法 160例患者随机分为对照组和观察组,每组80例,对照组给予前列舒通胶囊,观察组在对照组基础上加用前列康灌肠汤,疗程20 d.检测临床疗效、复发率、临床症状评分、血清及前列腺液炎症因子(TNF-α、IFN-γ、IL-1β、IL-8)、血液流变学指标(HBV、MBV、LBV、RV)变化.结果 观察组总有效率高于对照组(P<0.05),复发率更低(P<0.05).治疗后,2组临床症状评分、血清及前列腺液炎症因子、血液流变学指标降低(P<0.05),以观察组更明显(P<0.05).结论 前列舒通胶囊联合前列康灌肠汤可有效改善湿热瘀阻型Ⅲ型慢性前列腺炎患者临床症状,复发率低.

AIM To observe the clinical effects of Qianlie Shutong Capsules combined with Qianliekang De coction Enema on patients with typeⅢchronic prostatitis due to Damp heat and Blood stasis Accumulation.METHODS One hundred and sixty patients were randomly assigned into control group(80 cases)for 20 day ad ministration of Qianlie Shutong Capsules,and observation group(80 cases)for 20 day administration of both Qian lie Shutong Capsules and Qianliekang Decoction Enema.The changes in clinical efficacy,recurrence rate,clinical symptom score,serum and prostatic fluid inflammatory factors(TNF α,IFN γ,IL 1β,IL 8)and hemorheological indices(HBV,MBV,LBV,RV)were detected.RESULTS The observation group demonstrated higher total ef fective rate than the control group(P<0.05),along with lower recurrence rate(P<0.05).After the treatment,the two groups displayed decreased clinical symptom score,serum and prostatic fluid inflammatory factors and he morheological indices(P<0.05),especially for the observation group(P<0.05).CONCLUSION For the pa tients with typeⅢchronic prostatitis due to Damp heat and Blood stasis Accumulation,Qianlie Shutong Capsules combined with Qianliekang Decoction Enema can effectively improve clinical symptoms with low recurrence rate.