中风证素分布及与抑郁程度的相关性分析

Correlation of Traditional Chinese Medicine Syndrome Elements with Depression Degree in Stroke

目的分析中风中医证素分布情况,探讨中医证素与中风后抑郁的关系。方法采用回顾性调查法,选取120例缺血性中风病人,临床分为卒中后抑郁(PSD)组和非PSD组,收集中医临床资料,分析中医证素分布特点。结果肝郁出现频次最高,其次是阴虚、气虚。PSD组病人均存在肝郁证素;与非PSD组比较,PSD组肝郁证素比例较高,差异有统计学意义(P<0.01);PSD组和非PSD组其他各证素比例比较,差异无统计学意义(P>0.05)。肝郁积分与汉密尔顿抑郁量表评分呈正相关(r=0.898,P<0.01)。结论肝郁是中风的常见证素,肝郁积分与PSD病人抑郁程度呈正相关。

Objective To investigate correlation of traditional Chinese medicine syndrome elements with depression degree in stroke.Methods One hundred and twenty patients with ischemic stroke were divided into post-stroke depression(PSD)group and non-PSD group.Traditional Chinese medicine clinical datas and distribution characteristics of traditional Chinese medicine syndrome elements were selected by retrospective investigation.Results The distribution of traditional Chinese medicine syndrome elements had a decrease trend of Liver depression syndrome,Yin deficiency,and Qi deficiency.All patients in PSD group had Liver depression syndrome.Compared with non-PSD group,the proportion of Liver depression syndrome in PSD group had significant difference(P<0.01).Compared with non-PSD group,no obvious differences were observed concerning proportion of other traditional Chinese medicine syndrome elements in PSD group(P>0.05).There was a positive correlation between the score of Liver depression syndrome and Hamilton Depression Scale Score(r=0.898,P<0.01).Conclusion Liver depression syndrome was one of common traditional Chinese medicine syndrome elements in stroke,and the score of liver depression syndrome was related with depression degree of PSD patients.