精神分裂症采用齐拉西酮联合疏肝解郁胶囊治疗的观察

Observation of ziprasidone combined with Shuganjieyu capsule in the treatment of schizophrenia

目的探讨齐拉西酮和疏肝解郁胶囊联合治疗精神分裂症的临床疗效。方法将2018年1~12月我院收治的60例精神分裂患者进行分组调查研究,按照随机数字表法分为实验组(n=30)和对照组(n=30),单独使用齐拉西酮治疗的患者设为对照组,使用齐拉西酮和疏肝解郁胶囊联合治疗的患者设为实验组,对两组患者的临床治疗效果进行观察。结果给予两组患者不同的治疗方案后,实验组患者的治疗总有效率相较于对照组明显更高,差异有统计学意义(P<0.05);在阳性和阴性症状量表(PANSS)评分方面,实验组和对照组相比明显更低,差异有统计学意义(P<0.05);同时实验组患者的生活质量评分与对照组相比明显更高,差异有统计学意义(P<0.05)。结论对于精神分裂症患者的治疗应用齐拉西酮与疏肝解郁胶囊联合治疗能够有效提高患者的治疗效果,同时对于提高患者的生活质量也具有良好的促进作用,此方式值得临床应用和推广。

Objective To investigate the clinical efficacy of ziprasidone combined with Shuganjieyu capsule in the treatment of schizophrenia.Methods 60 patients with schizophrenia admitted to our hospital from January to December 2018 were divided into experimental group(n=30)and control group(n=30)according to the random number table method.The control group was treated with ziprasidone alone,and the experimental group was treated with ziprasidone and Shuganjieyu capsule.The clinical therapeutic effects of the two groups were observed.Results After the two groups of patients were given different treatment regimens,the total effective rate of treatment in the experimental group was significantly higher than that in the control group,and the difference was statistically significant(P<0.05).The positive and negative symptom scale(PANSS)scores of the experimental group were significantly lower than those of the control group.The comparison of the data showed that the difference was larger,and the difference was statistically significant(P<0.05).The quality of life scores of patients in the experimental group were significantly higher than those in the control group,and the difference was statistically significant(P<0.05).Conclusion The combination of ziprasidone and Shuganjieyu capsules for the treatment of schizophrenia can effectively improve the therapeutic effect of patients,and also has a good promotion effect on improving the quality of life of patients.Therefore,this method is worthy of clinical application and promotion.