2型糖尿病伴慢性牙周炎患者牙周炎症程度与血糖水平的关系

Relationship between periodontal inflammation degree and blood glucose level in patients with type 2 diabetes complicated with chronic periodontitis

目的探讨2型糖尿病伴慢性牙周炎患者牙周炎症程度与血糖水平之间的关系。方法选取我院口腔科门诊2016年7月~2018年6月诊治的慢性牙周炎伴2型糖尿病患者共189例为研究对象。依据牙周探诊深度及其牙周附着丧失的程度将患者分为轻度牙周病组及中重度牙周病组。对患者的牙周情况进行检查,并在其就诊时,对其糖化血红蛋白(HbAlC)、空腹血糖(FPG)进行检测,并观察患者牙周健康情况与血糖水平之间的关系。结果2型糖尿病合并牙周炎患者共189例,其中轻度牙周病患病率为25.93%,中重度牙周炎患病率为74.07%。轻度牙周病组的HbAlC(8.34±1.38)mmol/L,显著低于中重度牙周病组的(10.65±3.64)mmol/L,FPG为(8.17±1.30)mmol/L,显著低于中重度牙周病组的(10.43±3.57)mmol/L,差异具有统计学意义(P<0.05)。Logistic回归分析结果显示,2型糖尿病伴发慢性牙周炎的主要危险因素为HbAlC、FPG的升高(B=0.147、0.174,P<0.05),且HbAlC、FPG随着牙周病程度的加深而升高。结论2型糖尿病伴发慢性牙周炎主要影响因素为血糖的升高,且牙周病程度越严重,血糖越高。

Objective To explore relationship between periodontal inflammation degree and blood glucose level in patients with type 2 diabetes complicated with chronic periodontitis.Methods 189 patients with chronic periodontitis complicated with type 2 diabetes who were diagnosed and treated in the outpatient department of stomatology in our hospital from July 2016 to June 2018 were selected as the research objects.According to the depth of periodontal exploration and the degree of periodontal attachment loss,the patients were divided into the mild periodontal disease group and the moderate and severe periodontal disease group.The periodontal condition of the patients was examined,and their glycated hemoglobin(HbAlC)and Fasting blood glucose(FPG)were tested at the time of visit.The relationship between the periodontal health of patients and blood glucose levels was observed.Results There were 189 patients with type 2 diabetes complicated with periodontitis,of which the prevalence of mild periodontal disease was 25.93%and the prevalence of moderate to severe periodontitis was 74.07%.The HbAlC(8.34±1.38)mmol/L in the mild periodontal disease group was significantly lower than the(10.65±3.64)mmol/L in the moderate to severe periodontal disease group.The FPG of the mild periodontal disease group was(8.17±1.30)mmol/L,which was significantly lower than(10.43±3.57)mmol/L of the moderate to severe periodontal disease group.The difference was statistically significant(P<0.05).Logistic regression analysis showed that the main risk factors for type 2 diabetes complicated with chronic periodontitis were elevated HbAlC and FPG(B=0.147,0.174,P<0.05).Conclusion The main influencing factor of chronic periodontitis complicated with type 2 diabetes is an increase in blood glucose.The more severe the periodontal disease,the higher the blood glucose.