胎儿三维彩超联合胎儿颈项透明层检查在诊断胎儿颈部水囊状淋巴管瘤中的临床价值

The clinical value of three-dimensional color Doppler ultrasonography combined with nuchal translucency measurement in the diagnosis of fetal cervical hydrocystic lymphangioma

目的分析三维彩超联合胎儿颈项透明层(NT)检查在诊断胎儿颈部水囊状淋巴管瘤中的临床价值。方法将150例确诊为胎儿颈部水囊状淋巴管瘤的孕妇随机分为联合NT(n=50)、单独NT组组(n=50)和对照组(n=50),对照组用常规三维彩超诊断仪检查,联合组用三维彩超联合NT检查,单独NT组只用NT检查。分析诊断有效率、诊断学效能指标、淋巴管瘤的血流速度、胎儿NT和三组检测方法的异质性。结果三组间的诊断有效率、诊断学效能指标、瘤体静脉流速差异具有统计学意义(P<0.01);三组检测时峰值流速和阻力指数间差异具有统计学意义(P<0.05)。三组间特异度、敏感度、阳性比、阴性比和诊断比值间差异具有统计学意义(P<0.05)。结论三维彩超联合NT检查在胎儿颈部水囊状淋巴管瘤中诊断有效率较高。

Objective To analyze the clinical value of three-dimensional(3-D)color Doppler ultrasonography combined with nuchal translucency(NT)measurement in the diagnosis of fetal cervical cystic lymphangioma.Methods 150 pregnant women diagnosed with fetal cervical cystic lymphangioma were randomly divided into the joint NT group(n=50),single NT group(n=50)and control group(n=50).The control group received conventional 3-D color Doppler ultrasonography;the joint NT group received 3-D color Doppler ultrasonography joint with NT measurement;the single NT group received NT only.The effective diagnosis rate,diagnostic efficiency index,blood flow velocity of lymphangioma,transparent layer of fetal neck and heterogeneity of the three groups were analyzed.Results The effective rate,diagnostic efficiency index,blood flow velocity of lymphangioma were significantly different among the three groups(P<0.01),and the peak flow rate and resistance index were significantly different among the three groups(P<0.05).There were statistically significant differences in the specificity,sensitivity,positive ratio,negative ratio and diagnostic ratio among the three groups(P<0.05).Conclusions 3-D color Doppler ultrasonography combined with NT measurement is highly effective in the diagnosis of fetal cervical hydrocystic lymphangioma.