珠海市皮肤性病专科门诊就诊人群7种性传播疾病感染分析

Analysis of the infection of seven STD in the dermatology and STD clinics in Zhuhai

目的了解珠海市皮肤性病专科门诊就诊人群性传播疾病(STD)的感染情况,为临床性病的防治提供实验室依据。方法选取珠海市慢性病防治中心2015年至2017年皮肤科、性病科和妇科诊治患者,对沙眼衣原体(CT)、解脲支原体(UU)、人型支原体(MH)、梅毒(TP)、念珠菌(CA)、淋病奈瑟菌(NG)和人类免疫缺陷病毒(HIV)7种病原体(抗体)阳性率情况进行分析,统计分析剔除阳性复诊患者,同时统计分析混合感染和反复感染情况。结果3年共有6862人进行STD不同项目检查,7种病原体检测共有14828项,阳性1963项(13.2%),CT、NG、TP、HIV、UU、MH和CA病原体阳性率分别为14.2%、23.6%、11.1%、2.9%、31.9%、4.8%和17.3%,3年间STD病原体阳性率差异无统计学意义(P>0.05)。不同科室中,妇科送检病原体阳性率最高,为19.2%;不同性别中,女性患者的病原体总阳性率为19.3%,男性为9.8%,两者差异具有统计学意义(P<0.05),但男性CT、NG和HIV阳性率高于女性。患者混合感染率为2.5%,男性混合感染比女性高,但女性反复感染率高于男性。结论专科门诊就诊者7种病原体阳性率较高,女性病原体总阳性率高于男性,女性支原体、念珠菌反复感染现象较普遍,男性泌尿生殖道支原体和念珠菌感染应受到重视。加强对该类人群的性传播疾病的健康教育,引导就诊者进行STD联合筛查,对性传播疾病的防控具有重要意义。

Objective To understand the infection of sexually transmitted diseases(STD)in the dermatology and STD clinics in Zhuhai,in order to provide laboratory basis for the prevention and treatment of STD.Methods The infection rates of chlamydia trachomatis(CT),ureaplasma urealyticum(UU),mycoplasma homonis(MH),treponema pallidum(TP),candida(CA),neisseria gonorrhea(NG)and human immunodeficiency virus(HIV)was detected and analyzed in patients from the department of dermatology,STD and gynecology in Zhuhai Center for Chronic Disease Control from 2015 to 2017.Statistical analysis excluded positive patients in the follow-up visits.Meanwhile,the situation of mixed infection and repeated infection was analyzed.Results A total of 6862 patients received STD detection in the three years.14828 cases were detected for 7 pathogens and 1963 cases(13.2%)of them were positive.The positive rates of CT,NG,TP,HIV,UU,MH and CA were 14.2%,23.6%,11.1%,2.9%,31.9%,4.8%and 17.3%,respectively.There was no statistically significant difference in STD positive rate among the three years(P>0.05).The gynecology department had the highest positive rate(19.2%)among different departments.The positive rate of female(19.3%)was higher than that of male(9.8%),with statistically significant differences(P<0.05).However,the positive rates of CT,NG and HIV infection of male was higher than those of female.The total mixed infection rate of patients was 2.5%,and that of male was higher than female while the rate of repeated infection was significantly higher in female than that in male.Conclusions The detection rate of 7 pathogens is higher in the outpatients and the infection rate of female is significantly higher than that of male.The repeated infection rate of mycoplasma and candida is common in female and the infection of genitourinary tract mycoplasma and candida should be paid more attention to male.It is of great significance for the prevention and treatment of STD to strengthen health education for such population and guide patients to carry out STD associated screening.